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经皮穿刺置管引流与开腹手术引流治疗重症急性胰腺炎的对比研究 被引量:8

Comparative study of efficacy of percutaneous catheter drainage and direct laparotomy drainage in the treatment of severe acute pancreatitis
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摘要 目的比较使用经皮穿刺置管引流和直接开腹手术引流治疗重症急性胰腺疗效.方法回顾性分析我院2013年4月~2018年4月收治90例重症急性胰腺炎患者治疗资料,依据治疗方式将48例使用经皮穿刺置管引流治疗患者纳入研究组,42例使用直接开腹手术引流患者纳入对照组.比较两组患者治疗效果,疗效相关时间,治疗前后实验室指标变化,并发症发生率.结果研究组患者治疗总有效率为93.75%,对照组患者治疗总有效率为76.19%,两组患者总有效率比较差异具有统计学意义(P<0.05);研究组患者症状消失时间、血淀粉酶正常时间及住院时间均显著短于对照组患者(P<0.05);两组患者治疗后血钙、血糖、血淀粉酶、尿淀粉酶、静脉血WBC等实验室指标较治疗前显著改善(P<0.05),治疗后研究组患者血糖、血淀粉酶、尿淀粉酶显著低于对照组,(P<0.05),而治疗后两组血钙和静脉血WBC之间差异不显著(P>0.05);研究组患者并发症发生率(6.25%)显著低于对照组患者(P<0.05).结论重症急性胰腺炎治疗使用经皮穿刺置管引流疗效较好,可以显著改善患者血尿淀粉酶以及血糖水平,并发症发生较少,患者恢复较快. Objective To compare the efficacy of percutaneous catheter drainage and direct laparotomy drainage in the treatment of severe acute pancreas. Methods The treatment data of 90 patients with severe acute pancreatitis admitted to our hospital from April 2013 to April 2018 were retrospectively analyzed. According to the treatment methods, 48 patients with percutaneous catheter drainage were included in study group, and 42 patients with direct laparotomy drainage were included in control group. The treatment effects, efficacy-related time, laboratory indexes before and after treatment and incidence rate of complications were compared between the two groups. Results The total effective rate of treatment was 93. 75% in study group and 76. 19% in control group, and the difference in the total effective rate between the two groups was statistically significant ( P < 0. 05 ). The disappearance time of symptoms ,normal time of blood amylase and hospital stay in study group were significantly shorter than those in control group ( P < 0. 05 ). The laboratory indexes of blood calcium, blood glucose, blood amylase, urinary amylase and venous blood WBC in the two groups were significantly improved after treatment compared with those before treatment ( P < 0. 05), and the blood glucose, blood amylase and urinary amylase in study group after treatment were significantly lower than those in control group ( P < 0. 05), but there were no significant differences in the blood calcium and venous blood WBC between the two groups ( P > 0. 05 ). The incidence rate of complications in study group (6. 25%) was significantly lower than that in control group ( P < 0. 05 ). Conclusions Percutaneous catheter drainage has good efficacy in the treatment of severe acute pancreatitis, and it can significantly improve the blood urinary amylase and blood glucose levels, and it has few complications and fast recovery.
作者 王安朋 李新力 邸军 WANG An-peng;LI Xin-li;DI Jun(Department of General Surgery, the People's Hospital of Kaifeng City, Kaifeng 475002, China)
出处 《肝胆外科杂志》 2019年第2期140-143,共4页 Journal of Hepatobiliary Surgery
关键词 经皮穿刺置管引流 直接开腹手术引流 重症急性胰腺炎 疗效对比 percutaneous catheter drainage direct laparotomy drainage severe acute pancreatitis efficacy comparison
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