摘要
目的分析微生物检验泌尿系统的病原菌的检测结果及耐药性试验。方法回顾性分析700例泌尿系统感染患者的临床资料,观察患者微生物检验结果的病原菌分类情况及主要病原菌对常用抗菌药物耐药性试验的数据。结果 700例患者共检出病原菌745株,单一病原菌感染患者占比为93.57%;两种病原菌感染患者占比为6.43%。病原菌中革兰氏阴性菌394株,其中大肠艾希杆菌占比最高为37.05%,革兰氏阳性菌178株,其中鸟肠球菌占比最高为16.24%,假丝酵母菌173株,其中白假丝酵母菌占比最高为15.97%。大肠艾希杆菌对阿米卡星、阿莫西林、舒巴坦、头孢他啶及亚胺培南敏感度较高,亚胺培南最高为94.16%;鸟肠球菌对阿米卡星、阿莫西林、舒巴坦、头孢他啶及亚胺培南敏感度较高,舒巴坦最高为96.69%;白假丝酵母菌对头孢呋辛、青霉素G及替考拉宁敏感度较高,青霉素G最高为64.71%。结论泌尿系统感染患者的病原菌主要为革兰氏阴性与阳性病菌,不同种类的病原菌对于抗菌药物的敏感性不同,通过微生物检验方法确诊病原菌后,通过高敏感性抗菌药物的治疗,可以显著提高治疗效果,临床应用前景广泛。
Objective:to analyze the detection results and drug resistance test of pathogenic bacteria in the urinary system by microbial test.Methods: the clinical data of 700 patients with urinary tract infection were analyzed retrospectively, and the classification of pathogenic bacteria and the drug resistance test data of main pathogenic bacteria were observed.Results: a total of 745 strains of pathogenic bacteria were detected in 700 patients, and 93.57% of them were infected by a single pathogen.The proportion of patients infected with two kinds of pathogens was 6.43%.Among the pathogenic bacteria, there were 394 gram-negative strains, among which escherichia coli accounted for 37.05% and 178 gram-positive strains, among which enterococcus ornithoides accounted for 16.24% and candida albicans 173, among which candida albicans accounted for 15.97%.Escherichia coli was highly sensitive to amikacin, amoxicillin, sulbactam, ceftazidime and imipenem, with the highest level of imipenem being 94.16%.The sensitivity of enterococcus ornithae to amikacin, amoxicillin, sulbactam, ceftazidime and imipenem was higher, and the highest value of sulbactam was 96.69%.The sensitivity of candida albicans to cefuroxime, penicillin G and ticolanin was higher, and the highest of penicillin G was 64.71%.Conclusion: the pathogenic bacteria of patients with urinary system infection are mainly gram-negative and positive bacteria, and different types of pathogenic bacteria have different sensitivity to antimicrobial agents. After the pathogenic bacteria are confirmed by microbial test, the treatment with highly sensitive antimicrobial agents can significantly improve the therapeutic effect, and the clinical application prospect is wide.
作者
程志
CHENG Zhi(Dept.of laboratory,Shandong Zaozhuang mining group central hospital,Zaozhuang 277800,China)
出处
《泰山医学院学报》
CAS
2019年第8期596-598,共3页
Journal of Taishan Medical College
关键词
微生物检验
泌尿系统
病原菌
耐药性
microbial test
urinary system
pathogenic bacteria
drug resistance
