摘要
目的研究心理干预在治疗癌痛并伴有抑郁状态患者中的作用。方法选取我院肿瘤科2012年6月~2015年5月具有癌痛并伴有抑郁状态的恶性肿瘤患者168例,参考随机数字表法,按照1∶1比例将上述患者随机分为对照组和观察组,各84例。所有患者给予规范的癌痛三阶梯止痛治疗,观察组再联合心理干预治疗,包括药物治疗(艾司西酞普兰片)和心理疏导。记录两组患者疼痛数字分析法(NRS)、汉密尔顿抑郁量表(HAMD-17)、汉密尔顿焦虑量表(HAMA-14)评分和世界卫生组织生活质量评定量表(WHO?QOL)评分变化,分析心理干预在治疗癌痛中的作用。结果两组患者抑郁焦虑状态有所改善,但观察组疗效明显优于对照组(P<0.05);疼痛程度与抑郁情绪评分呈正相关(r=0.86,P<0.05);治疗后,两组NRS评分差异有统计学意义(P<0.05),接受心理干预的观察组疼痛缓解更明显(P<0.05)。结论癌痛和抑郁相互影响,心理干预可以提高癌痛患者止痛效果,提高患者生活质量。
Objective To study the role of psychological intervention in the treatment of cancer pain accompanied by depression. Methods 168 patients with malignant tumors who had cancer pain accompanied by depression in our hospital from June 2012 to May 2015 were selected. According to the random number table method, they were equally divided into the control group and the observation group, with 84 cases in each group. All patients were given standard three-step analgesic ladder treatment for cancer pain. The observation group was given psychological intervention on basis of it, including medication (escitalopram tablets) and psychological counseling. Changes in scores of Numerical Rating Scale (NRS), Hamilton Depression Scale (HAMD-17), Hamilton Anxiety Scale (HAMA-14) scores and the World Health Organization Quality of Life Rating Scale (WHO-QOL) in the two groups were recorded. The role of psychological intervention in the treatment of cancer pain was analyzed. Results The depression and anxiety status of the two groups were improved, but the curative effect of the observation group was significantly better than that of the control group (P < 0.05). The degree of pain was positively correlated with the depression score (r=0.86, P < 0.05). The NRS scores of the two groups were significantly different after treatment (P < 0.05). The pain relief was more obvious in patients who received psychological intervention in the observation group (P < 0.05). Conclusion Cancer pain and depression affect each other. Psychological intervention can improve the analgesic effect of patients with cancer pain and improve their quality of life.
作者
练英妮
欧庆连
陈玉兰
曾志坚
林雪梅
LIAN Yingni;OU Qinglian;CHEN Yulan;ZENG Zhijian;LIN Xuemei(Second Area of Oncology Department, the First People’s Hospital of Zhaoqing, Guangdong, Zhaoqing 526021, China)
出处
《中国医药科学》
2019年第13期175-178,共4页
China Medicine And Pharmacy
关键词
癌痛
抑郁
心理干预
止痛
Cancer pain
Depression
Psychological support
Analgesic
