摘要
目的探讨经尿道等离子前列腺剜除术治疗前列腺增生的有效性和安全性。方法选择2016年10月至2018年2月雅安市人民医院符合纳入标准的前列腺增生患者56例,随机分为采用经尿道等离子前列腺剜除术式(剜除组)和经尿道等离子前列腺电切术式(电切组),每组28例,分别对两组疗效指标进行比较。结果两组手术均获成功。两组术前年龄、前列腺体积、国际前列腺症状评分(international prostate symptom score, IPSS)、生活质量(quality of life,QOL)评分、最大尿流率等的差异无统计学意义(P>0.05)。与电切组比较,剜除组术中出血量更少[(80.50±19.25)ml比(106.50±15.83)ml,P=0.000],切除组织重量更多[(40.12±7.53)g比(34.48±10.83)g,P=0.028],术后膀胱冲洗时间[(1.10±0.88)d比(1.67±0.91)d,P=0.021]、术后拔尿管时间[(4.60±0.68)d比(5.50±0.83)d,P=0.000]及术后住院天数更短[(5.25±0.69)d比(6.90±1.14)d,P=0.000]。术中均未出现包膜穿孔、尿外渗等并发症。剜除组和电切组术后3个月IPSS[(5.60±2.18)分比(5.14±2.47)分,P=0.444],QOL评分[(1.30±0.60)分比(1.58±0.88)分,P=0.169],最大尿流率[(15.11±4.27)ml/s比(16.73±6.19)ml/s,P=0.259]的差异无统计学意义。剜除组发生尿道狭窄、出血、真性尿失禁分别为3、5、1例,电切组为2、3、0例。结论经尿道等离子前列腺剜除术治疗良性前列腺增生的有效性和安全性高于经尿道等离子前列腺电切术。
Objective To explore the efficiency and safety of transurethral plasmakinetics enucleation of the prostate(PKEP)in the treatment of benign prostatic hyperplasia(BPH). Methods From October 2016 to February 2018, 56 patients were diagnosed with BPH in Yaan People’s Hospital were randomly divided into PKEP group and transurethral resection of the prostate(TURP) group, 28 cases were in each group. The efficacy indicators between the two groups were compared. Results All operations were completed successfully. There were no significant differences in age, prostate volume, international prostate symptom score(IPSS), quality of life(QOL) score, and maximum urinary flow rate between the two groups(P >0.05). In PKEP group, the bleeding volume [(80.50±19.25) ml vs.(106.50±15.83)ml, P = 0.000] and the weight of the resected tissue [(40.12 ± 7.53)g vs.(34.48 ± 10.83)g, P = 0.028] were statistically significant than those in TURP group. In PKEP group, washing time [(1.10±0.88)d vs.(1.67±0.91) d, P = 0.021], postoperative urinary catheterization time[(4.60±0.68)d vs.(5.50±0.83)d, P = 0.000] and postoperative hospital stay were shorter[(5.25±0.69) d vs.(6.90±1.14) d, P = 0.000] than those in TURP group. There were no complications such as perforation of the capsule and extravasation of the urine during the operation. There were no significant differences in IPSS[(5.60 ± 2.18) vs.(5.14 ± 2.47), P = 0.444], QOL score[(1.30 ± 0.60) vs.(1.58±0.88), P = 0.169] and maximum urinary flow rate [(15.11±4.27) ml/s vs.(16.73±6.19) ml/s, P = 0.259] between the two groups. In PKEP group, true urinary incontinence, urethral stricture, hemorrhage occurred in 1, 3, 5 cases, respectively, and 0,2, 3 cases in TURP group. Conclusions The efficacy and safety of surgical treatment of BPH with PKEP is higher than with TURP.
作者
杜勇
李志远
何正宇
Du Yong;Li Zhiyuan;He Zhengyu(Department of Urology,Yaan People's Hospital,Yaan 625000,China)
出处
《北京医学》
CAS
2019年第7期556-558,共3页
Beijing Medical Journal
关键词
前列腺增生
经尿道等离子前列腺剜除术
经尿道等离子前列腺电切术
benign prostatic hyperplasia(BPH)
transurethral plasmakinetics enucleation of the prostate(PKEP)
transurethral resection of the prostate(TURP)
