摘要
目的探讨复位经皮螺钉内固定术对踝关节骨折患者的关节功能的改善效果与炎症水平的影响。方法回顾性分析2015年12月至2018年7月于本院治疗的86例踝关节骨折患者的临床资料,依据手术方案的不同,分为对照组(切开复位内固定术,43例)与观察组(复位经皮螺钉内固定术,43例),比较两组临床指标、关节功能及炎性因子水平[C反应蛋白(C-reactive protein,CRP)、白细胞介素-6(Interleukin6,IL-6)以及白细胞介素-8(Interleukin8,IL-8)]。结果 观察组术中失血量、手术时间、骨折愈合时间分别为(5.28±3.72)ml、(27.59±15.13)min、(2.97±1.06)个月,均低于对照组的(41.32±15.28)ml、(42.17±16.95)min、(3.58±1.64)个月,差异有统计学意义(均P < 0.05);术后6 个月,两组关节功能恢复效果对比,差异无统计学意义(P > 0.05);术后1 d,观察组CRP、IL-6 及IL-8 水平分别为(104.95±20.87)mg/L、(86.95±25.93)pg/L、(55.88±8.27)pg/L,均低于对照组患者的(135.27±31.28)mg/L、(112.35±25.67)pg/L、(59.76±9.25)pg/L,差异有统计学意义(均P < 0.05)。结论 踝关节骨折患者采用复位经皮螺钉内固定术治疗,可有效改善关节功能,减轻炎症反应,且可减少术中出血量,缩短骨折愈合时间。
Objective To investigate the effect of reduction and percutaneous screw internal fixation on joint function and inflammatory factor levels in patients with ankle fracture. Methods The clinical data of 86 patients with ankle fracture treated in our hospital from December, 2015 to July, 2018 were analyzed retrospectively. According to the different surgical schemes, they were divided into a control group (treated with open reduction and internal fixation) and an observation group (treated with percutaneous screw internal fixation), 43 cases for each group. The clinical indicators, joint function, and inflammatory factor levels [C reactive protein (C-reactive protein, CRP), white blood cell (leukocyte), interleukin 6 (IL 6), and interleukin 8 (IL 8)] were compared between the two groups. Results The intra-operative bleeding volume, operation time, and fracture healing time were (5.28 ±3.72) ml,(27.59 ±15.13) min, and (2.97 ±1.06) months in the observation group, and were (41.32 ±15.28) ml,(42.17 ±16.95) min, and (3.58 ±1.64) months in the control group, with statistical differences (all P < 0.05). 6 months after the operation, both groups recovered well in joint function, with no statistical differences between the two groups (P > 0.05). One day after the operation, the levels of CRP, IL-6, and IL-8 were (104.95 ±20.87) mg/L,(86.95 ±25.93) pg/L, and (55.88 ±8.27) pg/L in the observation group, and were (135.27 ±31.28) mg/L,(112.35 ±25.67) pg/L, and (59.76 ±9.25) pg/L in the control group, with statistical differences (all P < 0.05). Conclusion Reduction and percutaneous screw internal fixation for patients with ankle fracture can effectively improve joint function, reduce inflammatory reaction and intra-operative bleeding volume, and shorten fracture healing time.
作者
王海涛
刘剑
徐英智
Wang Haitao;Liu Jian;Xu Yingzhi(Shouguang People's Hospital,Shouguang 262700,China)
出处
《国际医药卫生导报》
2019年第15期2518-2521,共4页
International Medicine and Health Guidance News
关键词
踝关节骨折
复位经皮螺钉内固定术
关节功能
炎症因子水平
Ankle fracture
Reduction and percutaneous screw internal fixation
Joint function
Inflammatory factor levels
