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快速检测替代策略进行HIV感染诊断的可行性探讨 被引量:8

Feasibility study on the alternative strategy of rapid testing in the diagnosis of HIV infection in Yunnan Province
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摘要 目的探讨联合使用快速检测试剂用于HIV感染诊断在云南省全人群中推广应用的可行性。方法2017年1月-3月在云南省对1820份筛查阳性样品使用3种进口快速试剂和任意一种国产试剂进行检测.同时进行蛋白免疫印迹试验,蛋白免疫印迹试验结果不确定者进行随访或者核酸检测,对检测结果进行比对。结果4种快速检测试剂全有反应的1764份样品,其检测结果与HIV的感染状态的一致性为100%。结论联合使用4种快速试剂进行HIV感染诊断具有较高的特异性,可在全人群中推广运用。 Objective To explore the feasibility of the combined utilization of rapid testing reagents for the diagnosis of HIV infection in all population in Yunnan Province. Methods A total of 1 820 screening HIV positive samples were collected from January 2017 to March 2017 , which were tested using 3 kinds of imported rapid testing reagents and any kind of domestic rapid testing reagent, meanwhile which were tested with Western blot assay. HIV antibody indeterminate samples of Western blot were further subjected to following up or liIV RNA testing. Then the results of the two methods were compared. Results A total of 1 764 samples reacted with all the four kinds of rapid testing reagents, whose HIV infection status were confirmed with western blot assay, following-up or HIV RNA testing. Conclusion It has a high specificity to use 4 kinds of rapid testing reagents to diagnose HIV infection, which can be recommended to use in practice.
作者 杨敏 陈敏 陈会超 戴洁 董莉娟 马艳玲 YANG Min;CHEN Min;CHEN Hui-chao;DAI Jie;DONG Li-juan;MA Yan-ling(Institute for the Prevention and Control of Sex Transmitted Disease and AIDS y Yunnan Center far DiseaseControl arul Prevention , Kunming, Yunnan 650022, China)
出处 《中国卫生检验杂志》 CAS 2019年第17期2084-2085,2103,共3页 Chinese Journal of Health Laboratory Technology
关键词 艾滋病 快速检测 替代策略 AIDS Rapid testing Altemative strategy
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