摘要
大麻二酚(cannabidiol,CBD)是工业大麻中含量最丰富的大麻素,其不具有精神活性,基本无毒副作用,目前已被FDA批准用于治疗难治性癫痫,并且在炎症性以及增殖性疾病中显示出良好的治疗作用。近年来研究表明CBD在皮肤科具有良好的应用前景,可能有益于痤疮、皮炎、银屑病和皮肤肿瘤等疾病。因此,本文主要综述CBD的作用靶点及其在多种皮肤疾病中的治疗潜力,以期为CBD作为皮肤病的新疗法提供参考。
Cannabidiol ( CBD) is one of the most abundant cannabinoids in industrial cannabis plants. Because of its absence of psychoactive properties and exciting clinical trial results, now FDA has approved it for the treatment of refractory epilepsy. Its benefits for inflammatory and hyperproliferative disorders have also been demonstrated. Additionally, recent studies indicated potential applications of CBD in dermatology, including acne, dermatitis, psoriasis, and skin tumors. In this context, this article reviews the targets and potential applications of CBD in the treatments of dermatoses, providing a reference for CBD as a novel option for skin diseases.
作者
李焰梅
郝丹
蒋献
LI Yanmei;HAO Dan;JIANG Xian(Department of Dermatology,West China Hospital,Sichuan University,Chengdu 610041 ,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2019年第10期1202-1205,共4页
The Chinese Journal of Dermatovenereology
