摘要
目的 探讨弥漫性轴索损伤（DAI）的发病情况、影像学表现、诊断及处理方法,以提高临床疗效。方法 回顾性分析我院颅脑损伤抢救中心收治的223例DAI患者的临床和影像学资料。结果 本组患者中入院时GCS≤8分的共173例（7.6％）,其中GCS≤5分的有100例（44.8％）。本组的总死亡率为29.1％（65/223）,GCS≤5分的死亡率为43％（43/100）。亚低温治疗的患者,GCS平均为4.4分,死亡率为30.8％（12/39）。结论 DAI的诊断主要根据其临床表现结合CT、MRI资料。治疗上宜采用综合治疗方式。早期应用亚低温治疗能提高疗效,应在临床加以推广。
Objective To investigate the pathogenesis, imaging findings, diagnostic and therapeutic methods of diffuse axonal injury( DAI) in order to improve the clinical outcome. Methods The clinical data and imaging findings of 223 cases with DAI were analyzed retrospectively,who were admitted to the emergency center of brain injury in Tianjin Huanhu Hospital. Results Of all the patients, there were 173 cases (77. 6% ) whose Glasgow coma scales (GCS) were 8 or less on admission; and among them, there were 100 patients(44. 8% ) whose GCSs were 5 or less. The general mortality of this group was 29.1 % (65/223), but the mortality of those with GCS≤5 on admission was 43% (43/100) . Patients treated with mild hypothermia had a mean GCS of 4.4 on admission; their mortality was 30.8% (12/39). Conclusion The diagnosis of DAI is mainly based on the clinical appearance and the imaging findings. Comprehensive interventions should be applied to the treatment of DAI, and the outcomes will be better if patients receive mild hypothermia therapy at the early stage of DAI, so the mild hypothermia should be popularized in the treatment of DAI.
出处
《中华神经外科疾病研究杂志》
CAS
2002年第4期351-353,共3页
Chinese Journal of Neurosurgical Disease Research
关键词
弥漫性轴索损伤
诊断
外科手术
亚低温治疗
DAI
Diffuse axonal injury
Diagnosis
Surgical operations
Mild hypothermia therapy
