摘要
目的研究左氧氟沙星和普拉洛芬联合玻璃酸钠滴眼液在白内障超声乳化术后的应用效果,为患者的恢复提供临床指导。方法选取西安第四医院眼科2018年3~12月期间接诊的80例白内障患者作为研究对象,按照随机数表法将其分为观察组和对照组,每组40例,两组患者均进行常规检查与治疗,对照组采用左氧氟沙星+玻璃酸钠滴眼液联合治疗,而观察组在对照组治疗的基础上采用普拉洛芬联合治疗。分别于治疗前1 d和治疗30 d后检测记录两组患者的干眼症状评分(SPEED评分)、角膜荧光素染色评分(FLS评分)、生活满意度量表评分(SWLS量表评分)、泪膜破裂时间(BUT),并比较治疗后两组患者的总有效率和并发症发生情况。结果治疗后,观察组患者的总有效率为95.0%,明显高于对照组的80.0%,差异具有统计学意义(P<0.05);治疗前,两组患者的SPEED评分、FLS评分、SWLS量表评分以及BUT值比较差异均无统计学意义(P>0.05);治疗后,两组患者的SPEED评分、FLS评分均明显下降,且观察组患者下降程度明显大于对照组,SWLS量表评分、BUT值均明显升高,观察组患者升高程度均明显大于对照组,差异均具有统计学意义(P<0.05);观察组患者的并发症总发生率为2.5%,明显低于对照组的15.0%,差异具有统计学意义(P<0.05)。结论左氧氟沙星+普拉洛芬+玻璃酸钠滴眼液联合治疗白内障超声乳化术后可以延长泪膜破裂时间,改善干眼症状,降低并发症的发生率,提高患者生活质量,具有临床应用价值。
Objective To study the effect of levofloxacin and pralofen combined with sodium hyaluronate eye drops after cataract phacoemulsification,and to provide clinical guidance for the recovery of patients.Methods Eighty cataract patients in Department of Ophthalmology,the Fourth Hospital of Xi'an from March 2018 to December 2018 were selected as the research objects.They were randomly divided into observation group and control group according to random number table method,with 40 patients in each group.All patients were given routine examination and treatment.Patients in the control group were treated with levofloxacin and sodium hyaluronate eye drops,and those in the observation group were further treated with pralofen based on the treatment in the control group.The dry eye symptom score(SPEED score),corneal fluorescein staining score(FLS score),life satisfaction scale score(SWLS score),tear film rupture time(BUT)of the two groups were measured and recorded before treatment and 30 days after treatment respectively, and the total effective rate and complications of the two groups were compared after treatment. Results Aftertreatment, the total effective rate in the observation group was 95.0%, which was significantly higher than 80.0% in thecontrol group (P<0.05). Before treatment, there were no significant difference in SPEED score, FLS score, SWLS score,and BUT value between the two groups (P>0.05). After treatment, the SPEED score and FLS score of the two groupswere significantly decreased, and the descent degree of the observation group was significantly greater than that of thecontrol group;the scores of SWLS scale and BUT were significantly increased, and the increase degree of the observationgroup was significantly higher than that of the control group (P<0.05). The total incidence of complications in theobservation group was 2.5%, which was significantly lower than 15.0% in the control group (P<0.05). Conclusion Thecombination of levofloxacin, pralofen and sodium hyaluronate eye drops is effective in the treatment of cataract afterphacoemulsification, and it can prolong tear film rupture time, improve dry eye symptoms, reduce the incidence of complicationsand improve the quality of life of patients, which has clinical application value and is worth promoting.
作者
徐曼
肇莉莉
XU Man;ZHAO Li-li(Department of Ophthalmology,the Fourth Hospital of Xi'an City,Xi'an 710004,Shaanxi,CHINA)
出处
《海南医学》
CAS
2019年第16期2120-2123,共4页
Hainan Medical Journal
