摘要
目的探讨双水平气道正压通气联合固尔苏治疗新生儿呼吸窘迫综合征的疗效。方法回顾分析2015年4月—2018年4月该院收治的62例新生儿呼吸窘迫综合征患儿的临床资料,试验组给予双水平气道正压通气联合固尔苏治疗,参照组给予双水平气道正压通气治疗。结果试验组的PaO2、PaCO2、动脉肺泡氧分压比值分别为(69.98±11.39)mmHg、(42.36±8.24)mmHg、(0.27±0.15),对照组分别为(60.25±13.54)mmHg、(48.35±9.32)mmHg、(0.18±0.22),组间比较差异有统计学意义(t=14.250、5.690、3.540,P<0.05);试验组的上机时间、住院时间、静脉营养时间、失败人数分别为(4.51±1.32)d、(30.35±3.62)d、(20.01±3.21)d、5例,对照组分别为(5.86±0.86)d、(35.54±6.34)d、(25.36±3.64)d、12例,组间差异有统计学意义(t=3.840、5.620、10.210,P<0.05;χ^2=14.660,P<0.05)。结论对新生儿呼吸窘迫综合征患儿采取双水平气道正压通气,并联合使用固尔苏治疗的效果较好,安全性高,值得广泛推广。
Objective To investigate the efficacy of bi-level positive airway pressure combined with Guersu in the treatment of neonatal respiratory distress syndrome.Methods The clinical data of 62 patients with neonatal respiratory distress syndrome admitted to the hospital from April 2015 to April 2018 were retrospectively analyzed.The experimental group and the reference group were compared in the effect of treatment.The experimental group was given bi-level positive airway pressure combined with Guersu treatment,the reference group was given bi-level positive airway pressure therapy.Results The ratios of PaO2,PaCO2 and arterial alveolar oxygen partial pressure in the experimental group were(69.98±11.39)mmHg,(42.36±8.24)mmHg and(0.27±0.15),respectively.The control group was(60.25±13.54)mmHg and(48.35±9.32)mmHg,(0.18±0.22),the difference between groups was statistically significant(t=14.250,5.690,3.540,P<0.05);the observation time,hospitalization time,intravenous nutrition time,and number of failures in the experimental group were(4.51±1.32)d,(30.35±3.62)d,(20.01±3.21)d,5 cases,the control group were(5.86±0.86)d,(35.54±6.34)d,(25.36±3.64)d,12 cases,the difference between groups was statistically significant(t=3.840,5.620,10.210,P<0.05;χ^2=14.660,P<0.05).Conclusion The use of bilevel positive airway pressure in patients with neonatal respiratory distress syndrome,combined with the use of Guersu treatment,is effective and safe,and it is worthy of widespread promotion.
作者
蔡开晖
CAI Kai-hui(Department of Pediatrics,Dongshan County General Hospital,Zhangzhou,Fujian Province,363400 China)
出处
《中外医疗》
2019年第28期58-60,共3页
China & Foreign Medical Treatment
关键词
双水平气道正压通气
固尔苏
新生儿呼吸窘迫综合征
疗效观察
Bi-level positive airway pressure
Guersu
Neonatal respiratory distress syndrome
Therapeutic effect
