摘要
目的研究普萘洛尔辅助治疗甲亢病人的临床效果。方法选取94例甲亢患者,将其随机分为两组各47例,对照组采用甲巯咪唑(10mg,口服,tid)治疗,观察组加用普萘洛尔(10mg,口服,bid)治疗,3个月后比较两组的治疗效果、甲状腺激素变化情况及不良反应发生情况。结果观察组治疗有效率(95.74)高于对照组(80.85)(P<0.05);治疗后观察组血清游离甲状腺素(FT4)、血清游离三碘甲状腺原氨酸(FT3)水平低于对照组(P<0.05);观察组不良反应发生率(4.26%)低于对照组(21.28%)(P<0.05)。结论普萘洛尔辅助治疗甲亢可有效促进患者甲状腺激素水平恢复,效果显著,安全性良好。
Objective To study clinical effect of propranolol in adjuvant treatment of hyperthyroidism. Methods Choose 94 cases hyperthyroidism patients, divide them randomly into two groups, 47 cases in each group. Control group was treated with methimazole(10 mg, oral, tid) and observation group with propranolol(10 mg, oral, bid). Compare curative effect, thyroid hormone changes and adverse reactions of two groups after 3 months. Results Effective rate of treatment in observation group(95.74) was higher than control group(80.85)(P<0.05);serum free thyroxine(FT4) and free triiodothyronine(FT3) levels in observation group were lower than control group(P<0.05);adverse reactions incidence in observation group(4.26%) was lower than control group(21.28%)(P<0.05). Conclusion Propranolol adjuvant therapy can promote recovery of thyroid hormone level of hyperthyroidism patients effectively, with significant effect and good safety.
作者
赵丽英
ZHAO LI-ying(Santai County People's Hospital,Santai,Sichuan,621100)
出处
《智慧健康》
2019年第30期52-53,共2页
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