摘要
目的:探讨玻璃化冻存延期回植技术用于大面积撕脱皮肤伤的临床效果。方法:选择2015年6月至2018年6月收治的大面积皮肤撕脱伤的患者16例,根据处理方式分为撕脱皮肤玻璃化冻存二期回植组和撕脱皮肤一期回植组,每组8例患者。皮肤冻存后回植前,采用MTT法检测皮肤活力,比较两组皮片回植后的成活率、感染率、平均住院时间。结果:玻璃化冻存组皮肤冻存后平均活力为92.56%±7.20%,皮片成活率为81.74%±5.78%,感染率12.5%,平均住院时间33.13±3.91 d;一期皮肤回植组皮片成活率21.91%±5.28%,感染率100%,平均住院时间47.50±1.93 d。玻璃化皮肤保存组皮片成活率、感染率、平均住院时间均优于一期皮肤回植组(P<0.05)。结论:皮肤玻璃化冻存延期回植技术用于无法一期回植皮肤撕脱伤的临床效果较好。
Objective: To observe the clinical efficacy of delayed back grafting technique with vitrification cryopreservation skin in the treatment of serious avulsion injury. Methods: Patients suffered from serious skin avulsion from June 2015 to June 2018 were divided into two groups: the vitrification preservation group and the one-stage replanting group according the management method, 8 patients in each group. The cells viability of the skin before replanting after cryopreservation were evaluated using MTT. The skin survival rates, infection rates, average inhospital time were compared between the two groups. Results: The average cells viability of the skin before replanting after cryopreservation was 92.56%±7.20%. The skin survival rates was 81.74%±5.78%. The infection rates was 12.5%, and the average inhospital time was 33.13 ±3.91 d. The skin survival rates, infection rates, average inhospital time in the one-stage replanting group were 21.91% ±5.28%, 100%, 47.50 ±1.93 d. There is difference between the groups in the skin survival rates, infection rates, average inhospital time(P <0.05). Conclusion: The clinical effect of delayed back grafting technique with vitrification cryopreservation skin is good in the treatment of serious avulsion injury that skin can not be replanted one-stage.
作者
何志
李学拥
雷战军
赵卓伟
孟祥海
华振
李靖
黄辞
HE Zhi;LI Xue-yong;LEI Zhan-jun;ZHAO Zhuo-wei;MENG Xiang-hai;HUA Zhen;LI Jing;HUANG Ci(Department of Burns and Plastics Surgery,The Second Affiliated Hospital,Air Force Medical University of PLA,Xi'an,Shaanxi,710038,China;Department of Academic stdudies,The Second Affiliated Hospital,Air Force Medical University of PLA,Xi'an,Shaanxi,710038,China)
出处
《现代生物医学进展》
CAS
2019年第20期3866-3870,共5页
Progress in Modern Biomedicine
基金
国家自然科学基金项目(81272134)
关键词
皮肤撕脱伤
玻璃化皮肤保存
延期回植技术
Skin avulsion injury
Skin cryopreservation technique
The delayed back grafting technique
