摘要
目的:探讨针灸治疗慢性萎缩性胃炎的疗效及对炎症因子和生活质量的影响。方法:选择于我院就诊治疗的确诊为慢性萎缩性胃炎的120例患者作为研究对象,采用随机数字表法将其均分为观察组和对照组各60例,其中对照组给予院内常规西医治疗方法,观察组给予针灸治疗,比较两组临床治疗疗效、炎症因子水平变化和生活质量。结果:观察组总有效率为91.67%,显著高于对照组的75.00%,两组比较差异有统计学意义(P<0.05)。两组治疗后肿瘤坏死因子-α(Tumor Necrosis Factor,TNF-α)、白细胞介素(Interleukin,IL)-11及IL-8指标水平均显著低于治疗前,比较差异均有统计学意义(P<0.05),观察组治疗后TNF-α、IL-11及IL-8指标水平均显著低于对照组,两组比较差异均有统计学意义(P<0.05)。观察组心理功能、生理功能、活力、躯体功能、情感职能、社会功能、精神健康及总体健康等评分均显著优于对照组,比较差异均有统计学意义(P<0.05)。观察组不良反应总发生率为3.3%,显著低于对照组的20.0%,两组比较差异均有统计学意义(P<0.05)。结论:相较于常规西医治疗方法而言,针灸治疗对于慢性萎缩性胃炎患者而言,不仅可更加有效的提高临床治疗效果,而且还能保护胃黏膜,提高患者生活质量,故值得在临床中进一步推广应用。
Objective:To investigate efficacy of acupuncture on chronic atrophic gastritis,inflammatory factors and quality of life.Methods:120 patients were randomly divided into the observation group and control group,60 patients in each group.The control group was given routine western medicine.The observation group was given acupuncture.Results:The total efficiency in the observation group was 91.67%,was significantly higher than 75.0%in the control group(P<0.05).TNF-α,IL-11 and IL-8 in two groups were significantly lower than those before treatment(P<0.05).TNF-α,IL-11 and IL-8 in the observation group were better than the control group(P<0.05).The scores of psychological function,physiological function,vitality,physical function,emotional function,social function,mental health and overall health in the observation group were significantly better than the control group(P<0.05).The total incidence of adverse reactions in the observation group was 3.3%,was significantly lower than 20.0%in the control group(P<0.05).Conclusion:Compared with conventional Western medicine treatment,Acupuncture was effective on chronic atrophic gastritis,can protect the gastric mucosa and improve the quality of life,is worthy of promotion.
出处
《中医临床研究》
2019年第29期42-44,共3页
Clinical Journal Of Chinese Medicine
关键词
慢性萎缩性胃炎
针灸治疗
临床疗效
炎症因子
生活质量
Chronic atrophic gastritis
Acupuncture
Clinical efficacy
Inflammatory factors
Quality of life
