摘要
目的探讨全程营养管理联合同步放化疗治疗局部晚期宫颈癌的临床效果。方法选取2017年6月~2019年3月在信丰县人民医院肿瘤科接受治疗的90例宫颈癌患者作为研究对象,采用随机数字表法分为研究组(48例)和对照组(42例)。对照组患者采用单纯放化疗;研究组在同步放化疗的基础上,接受全程营养管理。比较两组患者治疗前后的体重变化、营养状态及近期疗效的差异。结果两组患者治疗前的体重比较,差异无统计学意义(P>0.05);治疗后,研究组患者的体重高于对照组,差异有统计学意义(P<0.05);研究组患者的营养达标率高于对照组,差异有统计学意义(P<0.05);研究组患者的客观缓解率高于对照组,差异有统计学意义(P<0.05)。结论全程营养管理可以减少同步放化疗宫颈癌患者的体重下降,降低患者发生营养不良的风险,并提高患者的近期疗效。
Objective To investigate the clinical effects of whole-course nutritional management combined with concurrent chemoradiotherapy for locally advanced cervical cancer.Methods A total of 90 patients with cervical cancer who were treated in Xinfeng People′s Hospital from June 2017 to May 2019 were selected as the subjects,and divided into study group(48 cases)and control group(42 cases)by random number table method.The patients in the control group received concurrent chemoradiotherapy only,while patients in the study group received whole-course nutritional management combined with concurrent chemoradiotherapy.The differences in body weight,nutritional status and short-term efficacy before and after treatment were compared between the two groups.Results There was no significant difference in the body weight between the two groups before treatment(P>0.05).After treatment,the weight of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).The nutritional compliance rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).The objective response rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Whole-course nutrition management can reduce the weight loss of patients with cervical cancer with concurrent chemoradiotherapy,reduce the risk of malnutrition,and improve the short-term efficacy of patients.
作者
卢辛辛
郑建清
LU Xin-xin;ZHENG Jian-qing(Department of Oncology,Xinfeng People′s Hospital,Jiangxi Province,Xinfeng 341600,China;Department of Radiation Oncology,the Second Affiliated Hospital of Fujian Medical University,Fujian Province,Quanzhou 362000,China)
出处
《中国当代医药》
2019年第32期75-77,81,共4页
China Modern Medicine
基金
福建医科大学附属第二医院苗圃基金项目(2017MP04)
关键词
宫颈癌
营养干预
放射治疗
预后分析
Cervical cancer
Nutritional intervention
Radiotherapy
Prognostic analysis
