摘要
目的探讨表观扩散系数(Apparent Diffusion Coefficient,ADC)直方图鉴别乳头状肾癌(Papillary Renal Cell Carcinoma,p RCC)与嫌色细胞肾癌(Chromophobe Renal Cell Carcinoma,Ch RCC)的价值。方法回顾性分析23例p RCC与20例Ch RCC的影像学资料。患者均行肾脏常规MRI平扫、增强扫描以及扩散加权成像(Diffusion-Weighted Imaging,DWI)检查。测量两组患者ADC直方图各参数值(包括:最小值、平均值、中位值、最大值、偏度值以及峰度值)。统计分析各参数差异及其诊断效能。结果 pRCC的ADC直方图最小值、平均值以及中位值均低于Ch RCC,而最大值高于Ch RCC(P<0.05)。p RCC以正偏态分布为主,而Ch RCC以负偏态分布为主,两者偏度值有统计学意义(P<0.05),而峰度值无统计学意义(P>0.05)。对pRCC与ChRCC的鉴别诊断效能分析提示,最大值的敏感度最优(91.30%),偏度值的特异度(80.00%)及曲线下面积最优(0.773)。结论全容积ADC直方图对鉴别pRCC与ChRCC具有一定的价值,为临床定性诊断提供了参考依据。
Objective To investigate the value of apparent diffusion coefficient(ADC) histogram in differentiating papillary renal cell carcinoma(pRCC) from chromophobe cell renal cell carcinoma(ChRCC). Methods The data of 23 cases of pRCC and 20 cases of ChRCC were analyzed retrospectively. Patients underwent conventional MRI scan, enhanced scan and diffusion weighted imaging(Diffusionweighted imaging DWI). The parameters of ADC histogram of the two groups were measured, including minimum, average, median, maximum, skewness and kurtosis. The differences of each parameter and their diagnostic efficacy were analyzed. Results The minimum, average and median values of ADC histogram of pRCC were lower than those of ChRCC, while the maximum values were higher than those of ChRCC(P<0.05). Positive skewness distribution was the dominant factor in pRCC, while negative skewness distribution was the dominant factor in ChRCC. The skewness of pRCC and ChRCC had statistical significance(P<0.05), but the kurtosis had no statistical significance(P>0.05). The discriminant diagnosis efficiency analysis of pRCC and ChRCC indicated that the sensitivity of maximum value was the best(91.30%), the specificity of skewness value(80.00%) and the area under curve(0.773) were the best. Conclusion ADC histogram has certain value in differentiating pRCC from ChRCC, and provides reference for clinical qualitative diagnosis.
作者
韩云
张跃
HAN Yun;ZHANG Yue(Department of Radiology,Wuhan No.1 Hospital,Wuhan Hubei 430022,China)
出处
《中国医疗设备》
2019年第12期72-75,共4页
China Medical Devices
关键词
全容积表观扩散系数直方图
乳头状肾癌
嫌色细胞肾癌
apparent diffusion coefficient histogram
papillary renal cell carcinoma
chromophobe renal cell carcinoma
