摘要
回顾性分析6例临床诊断为皮质基底节综合征(CBS)患者的临床及影像学资料。6例患者均表现为不对称的临床症状。认知功能障碍5例,情感障碍6例,皮层复合感觉异常2例,语言障碍5例,失用4例。6例患者均出现肌张力增高和肢体或躯干僵硬感,易跌倒4例,运动迟缓4例,震颤2例。头部磁共振成像(MRI)显示4例为单侧脑叶萎缩,2例为双侧海马轻度萎缩。4例正电子发射断层成像(PET)检查的患者均表现为单狈寸脑叶局限性葡萄糖代谢减低。PET检查有助于CBS的诊断。
The clinical and imaging data in 6 patients with corticobasal syndrome were retrospectively analyzed.Six patients presented asymmetric clinical symptoms,including 5 with cognitive impainnent,6 with emotional disorders,2 with cortical sensory deficit,5 with lalopathy,and 4 with apraxia.All patients developed limb dystonia and limb or trunk stiffness,4 with tumble,4 with bradykinesia,and 2 with tremor.Brain magnetic resonance imaging(MRI)showed that 4 patients had unilateral cerebral atrophy and 2 had mild atrophy of bilateral hippocampus.Localized low glucose metabolism in the unilateral cerebral lobe was seen in four patients by positron emission computed tomography(PET)examination,suggesting that PET is helpful for the diagnosis of corticobasal syndrome.
作者
孙庆利
杨琼
孙阿萍
傅瑜
樊东升
Sun Qingli;Yang Qiong;Sun Aping;Fu Yu;Fan Dongsheng(Department of Neurology,Perking University Third Hospital,Beijing 100191,China)
出处
《中华内科杂志》
CAS
CSCD
北大核心
2019年第12期905-907,共3页
Chinese Journal of Internal Medicine
