摘要
目的研究厦门市海沧地区女性泌尿生殖道支原体感染的现状及其耐药情况,为临床泌尿生殖道支原体感染的诊断和治疗提供客观依据。方法回顾性分析2018年1至2018年12月于厦门市海沧医院妇产科就诊的510例女性泌尿生殖道感染疑似患者的临床资料,对送检的阴道分泌物样本支原体培养及药敏试验的检测结果进行统计分析。结果510例女性泌尿生殖道感染疑似患者中,支原体阳性检出率为52.1%,其中,解脲脲原体(Uu)占支原体感染比例最高为80.8%,解脲脲原体+人型支原体(Uu+Mh)混合感染占支原体感染比例为15.1%,人型支原体(Mh)占支原体感染比例最低为4.1%;不同年龄组的支原体阳性检出率略有不同,≥50岁年龄组女性泌尿生殖道感染疑似患者的支原体阳性检出率最低为29.2%;药敏结果显示,支原体对9种抗菌药物的敏感情况各不相同,总敏感率以交沙霉素(99.2%)最高,其次为美满霉素(98.5%)和强力霉素(98.1%),氧氟沙星(13.6%)敏感率最低。结论厦门市海沧地区女性泌尿生殖道支原体感染类型以解脲脲原体感染为主,年龄<50岁女性支原体感染率较高,年龄≥50岁女性的支原体感染率较低;3种支原体感染情况均以交沙霉素、美满霉素、强力霉素的敏感率最高,故临床治疗女性泌尿生殖道支原体感染时应依据药敏试验结果合理应用抗菌药物,并首选这3种抗菌药物。
Objective To study the situaton and antibiotic susceptibility of Mycoplasma infection in female urogenital tract in Haicang district of Xiamen.Methods A retrospective analysis of the results of mycoplasma culture,identification and susceptibility test were detected on 510 cases of female suspected patients with urogenital tract infection were performed,from the gynaecology and obstetrics department of Haican hospital of Xiamen,from January 2018 to December 2018.Results The results of mycoplasma culture,identification and susceptibility test were collected and analyzed,in the 510 cases of female suspected patients with urogenital tract infection,the positive rate of mycoplasma was 52.1%,among which,Ureaplasma urealyticum(Uu)accounted for the highest proportion of Mycoplasma infection,was 80.8%.Ureaplasma urealyticum+Mycoplasma hominis(Mh+Uu)mixed infection,was 15.1%.Mycoplasma hominis(Mh)accounted for the lowest proportion of mycoplasma infection,was 4.1%.The positive rates of mycoplasma were slightly different in different age groups,the positive rate of group of female suspected patients with urogenital tract infection who aged than 50,was the lowest 29.2%.The antibiotic sensitivity of mycoplasma to 9 antibacterial drugs were different,the total sensitivity of josamycin was the highest(99.2%),followed by clarithromycin(98.5%)and doxycycline(98.1%).The antibiotic sensitivity of ofloxacin(13.6%)was the lowest.Conclusion Mycoplasma infection in female urogenital tract was mainly caused by Ureaplasma urealyticum,in Haicang district of Xiamen.The antibiotic sensitivity rate of josamycin,clarithromycin and doxycycline were the highest,in the three kinds of mycoplasma infections.So the three antibiotic drugs should be rationally predominant,according to the results of antibiotic sensitivity test,in treating mycoplasma infection in female urogenital tract.
作者
赵志伟
杨宁
宋曼莉
严荔贞
Zhao Zhiwei;Yang Ning;Song Manli;Yan Lizhen(Department of Clinical Laboratory,Haicang Hospital of Xiamen,Xiamen,Fujian,361026,China;Department of ICU,Haicang Hospital of Xiamen,Xiamen,Fujian,361026,China;Department of Gynaecology and Obstetrics,Haicang Hospital of Xiamen,Xiamen,Fujian,361026,China)
出处
《当代医学》
2019年第36期77-79,共3页
Contemporary Medicine
关键词
支原体感染
解脲脲原体
药敏试验
Mycoplasma infection
Ureaplasma urealyticum
Drug susceptibility test
