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轻微型肝性脑病发病机制的研究进展 被引量:11

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摘要 轻微型肝性脑病(MHE)指肝性脑病的初级阶段,常并发于急慢性肝功能衰竭或门体静脉分流异常的患者。MHE患者仅表现为轻微的神经认知缺陷,通常只能通过各种神经电生理和神经电心理测试才能发现,若不加以治疗可进展为显性肝性脑病。MHE的发病机制复杂,目前最常见的学说有氧化应激/亚硝化应激学说、炎性反应学说、氨中毒学说、氨基酸失衡学说、神经递质改变学说、锰中毒学说、幽门螺杆菌与肠道微生物失衡学说等,此外还有低钠血症学说、锌缺乏理论、褪黑素学说等,多种学说相互影响、相互补充。
出处 《山东医药》 CAS 2019年第35期103-105,共3页 Shandong Medical Journal
基金 安徽省科技攻关计划项目(1401045019)
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