摘要
目的探讨经颅彩色双功能超声(TCCS)在评估类风湿性关节炎(RA)患者脑动脉硬化中的临床价值。方法选取RA患者和健康体检者各50例,应用TCCS测量大脑中动脉收缩期峰值速度(PSV)、舒张末期速度(EDV)、搏动指数(PI)、阻力指数(RI),计算收缩期平均速度(AS)、反弹高度(RH)、紧张度(TD)、缓慢指数(SI)、压力指数(PI’)、血管负荷(VI),并分析RA患者血流动力学参数与病程的相关性。结果两组PSV、EDV、PI、RI比较差异均无统计学意义;RA组AS、RH、SI、TD低于对照组,PI’、VI明显高于对照组,差异均有统计学意义(均P<0.05)。RA患者PI’、VI与病程均呈正相关(r=0.385,0.565,均P<0.05)。结论应用TCCS检测RA患者大脑中动脉血流动力学的变化,有助于早期发现RA患者脑动脉硬化,为临床及早干预提供依据。
ObjectiveTo investigate the application value of transcranial color-coded duplex sonography(TCCS)in patients with rheumatoid arthritis(RA)for detection of cerebral atherosclerotic.MethodsFifty cases of RA patients were enrolled as RA group,50 cases of healthy volunteers as control group.Peak systolic blood flow velocity(PSV),end-diastolic velocity(EDV),pulsative index(PI),resistance index(RI)were measured by TCCS,average speed(AS),resistance height(RH),tensity degree(TD),pressure index(PI’),slowdown index(SI)and vascular load(VI)were calculated,and the correlations of the hemodynamic parameters and disease duration in RA patients were analyzed.ResultsThere was no significant difference in PSV,EDV,PI,RI between two groups.AS,RH,SI,TD were significantly lower,and PI’,VI markedly were significantly higher in RA group compared with the control group(all P<0.05).The disease duration had positive correlation with PI’and VI(r=0.385,0.565,both P<0.05).ConclusionThe application of TCCS in RA patients with hemodynamic changes of MCA could be a relatively sensitive tool for the detection of cerebral atherosclerotic lesions.It could enable timely intervention for early clinical reference.
作者
谢娟娟
陈红天
敖琨
张萍
龙湘党
XIE Juanjuan;CHEN Hongtian;AO Kun;ZHANG Ping;LONG Xiangdang(Department of Ultrasound,Hunan Provincial People’s Hospital,Changsha 410005,China)
出处
《临床超声医学杂志》
CSCD
2019年第12期948-950,共3页
Journal of Clinical Ultrasound in Medicine
关键词
超声检查
双功能
经颅
类风湿性关节炎
大脑中动脉
动脉硬化
Ultrasonography,difunctional,transcranial
Rheumatoid arthritis
Middle cerebral artery
Artery atherosclerosis
