摘要
目的探讨≤3 cm的周围型空洞型肺腺癌的CT征象及临床病理特征。方法回顾性分析2015年1月至2017年12月本院51例经胸部CT及手术病理确诊的≤3 cm周围型空洞型肺腺癌患者的胸部CT图像及临床病理资料,并对厚壁空洞与薄壁空洞的CT征象及临床病理特征进行对比,其中男29例、女22例,年龄62(56,67)岁。结果51例患者中厚壁空洞27例,薄壁空洞24例。厚壁空洞型腺癌有更大的SUVmax[6.5(3.7,9.7)vs.2.2(1.4,3.8),P=0.019]、空洞壁厚度[(11.8±4.6)mm vs.(7.6±3.7)mm,P=0.001]、肿瘤组织大小[2.1(1.7,2.8)cm vs.1.6(1.2,2.0)cm,P=0.006],更多的实性结节(17例vs.8例,P=0.035)。而薄壁空洞型腺癌有更多的吸烟史(12例vs.6例,P=0.038)、更大的空洞大小[12.3(9.2,16.6)mm vs.4.4(2.8,7.1)mm,P=0.000]及空洞所占比例[0.30(0.19,0.37)vs.0.03(0.01,0.09),P=0.000],CT上多表现为空洞内壁不光整(19例vs.6例,P=0.000)、空洞内分隔(16例vs.6例,P=0.001)、空洞内血管穿行(10例vs.1例,P=0.001)。结论胸部CT示≤3 cm的周围型空洞型肺腺癌在临床、影像、病理中具有特征性的表现,并且厚壁空洞型肺腺癌与薄壁空洞型肺腺癌之间具有明显的差异。
Objective To investigate the CT signs and clinicopathological features of peripheral cavitary lung adenocarcinoma with the largest diameter less than or equal to 3 cm.Methods From January 2015 to December 2017,the CT signs and clinicopathological fertures of 51 patients with≤3 cm peripheral cavitary lung adenocarcinoma diagnosed by chest CT and surgical pathology were retrospectively analyzed.Furthermore,CT signs and clinicopathological features of thick-walled cavitary lung adenocarcinoma and thin-walled cavitary lung adenocarcinoma were compared.There were 29 males and 22 females at age of 62(56,67)years.Results There were 27 thick-walled cavitary lung adenocarcinoma and 24 thin-walled cavitary lung adenocarcinoma.Thick-walled cavitary adenocarcinoma had greater SUVmax[6.5(3.7,9.7)vs.2.2(1.4,3.8),P=0.019],larger cavity wall thickness(11.8±4.6 mm vs.7.6±3.7 mm,P=0.001),larger tumor tissue size[2.1(1.7,2.8)cm vs.1.6(1.2,2.0)cm,P=0.006],and more solid nodules(17 patients vs.8 patients,P=0.035).Thin-walled cavitary adenocarcinoma had more smoking history(12 patients vs.6 patients,P=0.038),larger cavity size[12.3(9.2,16.6)mm vs.4.4(2.8,7.1)mm,P=0.000],and larger proportion of cavities[0.30(0.19,0.37)vs.0.03(0.01,0.09),P=0.000].On CT signs,there were more features of irregular inner wall(19 patients vs.6 patients,P=0.000),intra-cystic separation(16 patients vs.6 patients,P=0.001)and vessels through the cystic cavity(10 patients vs.1 patient,P=0.001)in thin-walled caviraty lung adenocarcinoma.Conclusion Peripheral cavitary lung adenocarcinoma of≤3 cm on chest CT has characteristic manifestations in clinical,imaging and pathology,and there is a statistical difference between thick-walled cavitary lung adenocarcinoma and thin-walled cavitary lung adenocarcinoma.
作者
刘展
张真榕
孙宏亮
刘德若
LIU Zhan;ZHANG Zhenrong;SUN Hongliang;LIU Deruo(Department of Thoracic Surgery,China-Japan Friendship Hospital,Peking University China-Japan Friendship School of Clinical Medicine,Beijing,100029,P.R.China;Department of Radiology,China-Japan Friendship Hospital,Peking University China-Japan Friendship School of Clinical Medicine,Beijing,100029,P.R.China)
出处
《中国胸心血管外科临床杂志》
CAS
CSCD
2020年第1期45-51,共7页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
关键词
肺腺癌
空洞
CT
病理
Lung adenocarcinoma
cavity
computed tomography
pathology
