参芪解毒汤辅助治疗糖尿病肾病Ⅳ期疗效观察被引量：1

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摘要目的:观察参芪解毒汤联合缬沙坦胶囊治疗糖尿病肾病IV期的临床疗效。方法:选取2017年5~12月于广宁县人民医院肾病科接受治疗的糖尿病肾病IV期患者47例,按照随机数表法分为对照组(23例)和观察组(24例)。对照组予以缬沙坦胶囊治疗,观察组在对照组治疗的基础上予以参芪解毒汤辅助治疗。比较两组临床疗效、肾功能指标、治疗前后24h尿蛋白、白介素-6(IL-6)与肿瘤坏死因子-α(TNF-α)。结果:观察组治疗总有效率高于对照组(P<0.05)。治疗后,观察组肾功能优于对照组(P<0.05);24h尿蛋白、白介素-6及肿瘤坏死因子-α水平均低于对照组(P<0.05);中医证候积分低于对照组(P<0.05)。结论:参芪解毒汤联合缬沙坦胶囊治疗糖尿病肾病IV期临床疗效明显优于单用缬沙坦胶囊治疗,值得在临床推广应用。

作者李丽兰冯仲成

机构地区佛山市第三人民医院广宁县人民医院

出处《内蒙古中医药》 2019年第12期3-5,共3页 Inner Mongolia Journal of Traditional Chinese Medicine

基金肇庆市科技创新指导类项目(201704031116)

关键词参芪解毒汤缬沙坦胶囊糖尿病肾病IV期白介素-6 肿瘤坏死因子-Α 疗效观察

分类号 R587.2 [医药卫生—内分泌]

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