摘要
目的观察中药灌肠联合按摩辅助治疗新生儿高胆红素血症的临床疗效。方法选取2016年1月至2018年1月于宁波市奉化区妇幼保健院二病区儿科收治的新生儿高胆红素血症76例,采用随机数字表法分为治疗组与对照组,各38例。对照组口服苯巴比妥片、可拉明,每日2~3次;酸中毒者予5%碳酸氢钠纠正,并使用XHZ-90新生儿黄疸治疗仪进行间断性蓝光照射,治疗8~12 h,间断12~16 h。治疗组在对照组治疗2 d后进行中药灌肠,并顺时针按摩腹部。2组均连续治疗7 d后统计疗效。结果对照组总有效率为76.3%,治疗组为92.1%,2组比较,差异有统计学意义(P<0.05)。治疗组黄疸持续时间、胎粪排尽时间和光疗时间均明显短于对照组,2组比较,差异均有统计学意义(P<0.05或P<0.01)。治疗后2组黄疸指数(TCB)、血清总胆红素(TBIL)、血清直接胆红素(DBIL)、内毒素(LPS)水平均较同组治疗前显著下降,且治疗组下降更显著,差异均有统计学意义(P<0.05)。结论中药灌肠联合按摩辅助治疗新生儿高胆红素血症,可促进患儿胆红素尽早排出,黄疸消退,值得临床推广应用。
Objective To observe the clinical efficacy of Chinese herbal enema combined with massage in adjuvant treatment of neonate hyperbilirubinemia.Methods Seventy-six cases of neonate hyperbilirubinemia admitted to pediatrics department in the second ward of Fenghua District Maternal and Child Health Hospital of Ningbo from January 2016 to January 2018 were divided into treatment group and control group according to random number table method,with 38 cases in each.The control group received oral phenobarbital tablets and coramine,2 to 3 times a day;the patients with acidosis was corrected with 5%sodium bicarbonate,and XHZ-90 neonate LED Phototherapy System and Accessories was used for intermittent blue light irradiation for 8-12 hours,intermittent 12-16 hours.The treatment group was given Chinese herbal enema combined with massage on the abdomen clockwise after the control group was treated for 2 days.We kept statistics about the curative effects after the 2 groups were consecutively treated for 7 days.Results The total effective rate of the control group was 76.3%,that of the treatment group was 92.1%,and the difference between the two groups was statistically significant(P<0.05).The jaundice duration,the defecation time of complete meconium and irradiation time of the treatment group were all shorter than those of the control group,and the difference was statistically significant between the two groups(P<0.05 or P<0.01).After treatment,the levels of transcutaneous bilirubin(TCB),serum total bilirubin(TBIL),serum direct bilirubin(DBIL)and lipopolysaccharide(LPS)in the two groups decreased significantly than those in the same group before treatment,moreover,the treatment group decreased more significantly,and the difference was statistically significant(P<0.05).Conclusion Chinese herbal enema combined with massage in adjuvant treatment of neonate hyperbilirubinemia can promote the early excretion of bilirubin and jaundice extinction,which is worthy of clinical promotion and application.
作者
肖建娜
XIAO Jianna(Department of Pediatrics,The Second Ward of Fenghua District Maternal and Child Health Care Hospital of Ningbo,Ningbo,Zhejiang,315500,China)
出处
《中医儿科杂志》
2019年第6期105-108,共4页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
高胆红素血症
新生儿
中药灌肠
按摩
临床观察
hyperbilirubinemia
newborn
Chinese herbal enema
massage
clinical observation
