摘要
目的:分析超高效液相色谱法检验利福平药物的效果和价值。方法:取60片利福平药物,根据不同的检验方法分为两组进行研究,对照组(30片)采用高效液相色谱法检验,观察组(30片)采用超高效液相色谱法进行检验,比较两组的检验结果。结果:药物平均分析时间比较,观察组为(3.11±0.38)min,对照组为(14.63±3.25)min,观察组药片平均分析时间明显短于对照组;观察组的药片彻底分离率为100%,对照组为83.33%,观察组药片彻底分离率明显高于对照组,两组比较差异均为(P<0.05)。结论:超高效液相色谱法在药物检验中,有效提高检验效率和质量,具有重要的推广应用价值。
Objective: To analyze the effect and value of ultra-high performance liquid chromatography(HPLC)in the determination of rifampicin. Methods: 60 tablets of rifampicin were divided into two groups according to different test methods. The control group(30 tablets)was tested by high performance liquid chromatographyand the observation group(30 tablets)was tested by ultra-high performance liquid chromatography. The results of the two groups were compared. Results: The average analysis time of drugs in the observation group was(3.11±0.38)min, the average analysis time of the tablets in the observation group was(14.63±3.25)min, and the complete separation rate of the tablets in the observation group was significantly shorter than that in the control group. The complete separation rate of the observation group was significantly higher than that of the control group(P<0.05). Conclusion: Ultra-high performance liquid chromatographycan effectively improve the efficiency and quality of drug detection, and has important value of popularization and application.
作者
袁文彬
YUAN Wen-bin(Clinical Laboratory,Jishui County Center for Disease Control and Prevention,Ji’an Jiangxi 331600,China)
出处
《药品评价》
CAS
2019年第20期74-75,共2页
Drug Evaluation
