摘要
近年来兴起的时差成像技术在为胚胎发育提供稳定培养环境的同时可通过拍摄系统全程记录植入前胚胎的动态发育过程,从而获得更加全面准确的胚胎发育信息。这些信息能够显示人类胚胎行为学及动力学指标,建立胚胎评估模型,能有效地克服形态学评估主观性大、所提供信息有限的弊端,成为胚胎评估更为有利的手段。本文总结了时差成像技术建立的参数与模型,及其在胚胎评估中的临床应用。
Time-lapse imaging technology developed in recent years can provide a more stable culture environment for embryos and record the dynamic development of preimplantation embryos through a camera system,thus providing more comprehensive and accurate information on embryonic development.Through this information,we can obtain human embryonic behavioral and kinetic parameters,and set up an embryo evaluation model,which can effectively overcome the disadvantages of the subjectivity of morphological evaluation and the limited information provided,and become a more favorable means for embryo evaluation.This paper summarizes the parameters and models of time difference imaging and its application in embryos and its clinical application in embryo evaluation.
作者
陈龙彬
顾亦凡
林戈
Chen Longbin;Gu Yifan;Lin Ge(Institute of Reproductive and Stem Cells,School of Basic Medicine,Central South University,Changsha 410000,China;CITIC Xiangya Reproductive and Genetic Hospital,Changsha 410000,China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2019年第11期951-955,共5页
Chinese Journal of Reproduction and Contraception
关键词
受精
体外
时差成像
胚胎评估
体外培养
Fertilization in vitro
Time-lapse imaging
Embryo evaluation
In vitro culture
