摘要
目的观察新生儿坏死性小肠结肠炎采取培菲康联合西咪替丁的临床效果。方法选取2014年2月至2019年2月苏州市第九人民医院新生儿科收治的60例新生儿坏死性小肠结肠炎,按数字表法分为对照组与研究组,各30例。对照组采取培菲康治疗,研究组在对照组基础上加用西咪替丁治疗。分析比对两组患儿临床疗效。结果研究组CD4^+、CD4^+/CD8^+水平高于对照组(P<0.05),治疗后两组CD8^+水平差异无统计学意义(P>0.05);研究组的临床疗效高于对照组,差异有统计学意义(P<0.05)。结论培菲康联合西咪替丁对新生儿坏死性小肠结肠炎具有积极意义,可提升治疗效果,改善胃肠道内环境,加强抵抗力。
Objective To analyze the clinical effect of bifikang combined with cimetidine in the treatment of neonates with necrotizing enterocolitis.Methods A total of 60 cases of neonatal necrotizing enterocolitis admitted to the Department of Neonatology of the Ninth People's Hospital of Suzhou City from February 2014 to February 2019 were divided into reference group and research group according to the digital table method,30 cases in each group.The control group was treated with Bifikang,and the research group was treated with cimetidine based on this,and the clinical efficacy of the patients was divided into two groups.Clinical effect of two groups of children were analyzed and compared.Results The levels of CD4^+,CD4^+/CD8^+in the study group were higher than those in the reference group(P<0.05),and there was no significant difference between the two groups after treatment(P>0.05);the clinical efficacy of the study group was higher than that of the reference group(P<0.05).Conclusion The combination of bifikang and cimetidine has a positive effect on neonatal necrotizing enterocolitis.It can improve the therapeutic effect,gastrointestinal environment and resistance.
作者
顾震宇
GU Zhenyu(Ninth People's Hospital of Suzhou,Suzhou,Jiangsu 215200,China)
出处
《大医生》
2019年第16期136-137,共2页
Doctor
