摘要
目的探讨彩色多普勒超声评价糖尿病视网膜病变非增殖期黄斑水肿患者眼球后动脉血流动力学的价值。方法选取2型糖尿病非增殖期黄斑水肿患者30例(46只眼)为病例组,2型糖尿病非增殖期视网膜病变患者30例(60只眼)为对照组,应用彩色多普勒超声检测两组视网膜中央动脉(CRA)、眼动脉(OA)、睫状后短动脉(PCA)的血流参数,并对其结果进行对比分析。绘制受试者工作特征(ROC)曲线分析各血流参数对糖尿病黄斑水肿的诊断价值。结果病例组CRA、PCA血流频谱均较对照组低平、圆钝,病例组OA血流频谱与对照组相似。病例组CRA的收缩期峰值流速(PSV)、舒张末期流速(EDV)及阻力指数(RI)均较对照组减低,差异均有统计学意义(均P<0.05);病例组PCA的PSV、EDV均较对照组减低(均P<0.05),RI与对照组比较差异无统计学意义;病例组OA的各血流参数与对照组比较差异均无统计学意义。以CRA的PSV 7.655 cm/s、EDV 2.925 cm/s及RI 0.645为截断值,诊断黄斑水肿的敏感性分别为80.0%、60.7%及63.8%,特异性分别为76.1%、76.1%及70.0%,曲线下面积分别为0.783、0.720及0.692。以PCA的PSV8.75 cm/s、EDV 2.56 cm/s为截断值诊断黄斑水肿的敏感性分别为75.0%、81.3%,特异性分别为61.4%、60.9%,曲线下面积分别为0.536、0.533。结论彩色多普勒超声可以监测糖尿病非增殖期黄斑水肿患者眼球后动脉血流动力学的改变,为临床早期治疗提供可靠依据。
ObjectiveTo investigate the value of color Doppler ultrasound in the evaluation of hemodynamics of posterior ophthalmic artery in diabetic retinopathy patients with nonproliferative macular edema.MethodsThirty patients(46 eyes) with nonproliferative macular edema of type 2 diabetes mellitus(case group) and 30 patients(60 eyes) with nonproliferative retinopathy of type 2 diabetes mellitus(control group)were selected. The blood flow parameters of central retinal artery(CRA),ophthalmic artery(OA)and posterior ciliary artery(PCA)were measured by color Doppler ultrasound.The diagnostic value of blood flow parameters for diabetic macular edema was analyzed by drawing the ROC curve.ResultsThe blood flow spectrums of CRA and PCA in the case group were lower and blunt than those in the control group,and the blood flow spectrums of OA in the case group were similar to those in the control group.The systolic blood flow velocity(PSV),end diastolic blood flow velocity(EDV)and resistance index(RI)of CRA in the case group were lower than those in the control group,and the differences were statistically significant(all P<0.05).PSV and EDV of PCA in the case group were lower than those in the control group(both P<0.05),RI of PCA in the case group had no significant difference compared with that in the control group.There was no significant difference in all parameters of OA between the case group and the control group.The optimal cutoff values of PSV,EDV and RI of CRA were 7.655 cm/s,2.925 cm/s and 0.645,respectively,the corresponding sensitivity and specificity were 80.0%,60.7%,63.8% and 76.1%,76.1% and 70.0%,respectively,the area under ROC curve were 0.783,0.720 and 0.692,respectively.The optimal cutoff values of PSV,EDV of PCA were 8.75 cm/s,2.56 cm/s,respectively,the corresponding sensitivity and specificity were 75.0%,81.3% and 61.4%,60.9%,respectively,the area under ROC curve were 0.536,0.533,respectively.ConclusionColor Doppler ultrasound can monitor the hemodynamic changes of the retrobulbar artery in diabetic patients with nonproliferative macular edema,which provide a reliable basis for early clinical treatment.
作者
安娟
红华
AN Juan;HONG Hua(Health Management Center,Inner Mongolia Autonomous Region People’s Hospital,Hohhot City 010070,China)
出处
《临床超声医学杂志》
CSCD
2020年第1期13-16,共4页
Journal of Clinical Ultrasound in Medicine
基金
内蒙古自治区自然科学基金项目(2017MS0803)
关键词
超声检查
多普勒
彩色
黄斑水肿
糖尿病
2型
球后动脉
血流动力学
Ultrasonography,Doppler,color
Macular edema,diabetes mellitus,type 2
Posterior ophthalmic artery
Hemodynamics
