摘要
组织细胞坏死性淋巴结炎(HNL)又名Kikuchi-Fujimoto病(KFD),是一种全身性疾病,典型临床表现为发热、淋巴结肿大及白细胞减少。KFD累及中枢和周围神经系统者较少见,可表现为无菌性脑膜炎、脑脊髓炎、周围神经病、小脑性共济失调以及震颤等。以神经系统症状为主要临床表现的KFD患者容易被误诊误治,因此笔者现主要围绕KFD累及神经系统的临床表现及相关鉴别诊断的研究进展进行综述,以期进一步指导KFD的临床诊治。
Histiocytic necrotic lymphadenitis is known as Kikuchi-Fujimoto disease(KFD).KFD is a systemic disease,which is characterized by fever,necrotizing lymphadenopathy and leukopenia.However,involvement of the central and peripheral nervous system is rare.It can present as aseptic meningitis,encephalomyelitis,peripheral neuropathy,cerebellar ataxia and tremor,which makes it difficult to be differentiated with other nervous system diseases.Our review summarizes the clinical manifestations and differential diagnoses of KFD involving nervous system in order to reduce misdiagnoses and mistreatments.
作者
杨佳蕾
王磊
陈华蕾
徐芳
尹世敏
Yang Jialei;Wang Lei;Chen Hualei;Xu Fang;Yin Shimin(Department of Neurology,Stroke Care and Research Center of People's Liberation Army,Rocket Force Characteristic Medical Center of People's Liberation Army,Beijing 100088,China;School of Basic Medical Science,Shandong First Medical University,Taian 271000,China)
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2020年第1期79-83,共5页
Chinese Journal of Neuromedicine
基金
国家自然科学基金青年基金(81801161)。
