摘要
目的探讨急性脑梗死合并2型糖尿病患者微栓子与血清脂蛋白相关磷脂酶A2(LpPLA2)的关系。方法选择2017年9月至2019年5月我院收治的120例急性脑梗死患者,根据有无糖尿病分为有2型糖尿病的DACI组(50例)和无2型糖尿病的NDACI组(70例)。对所有患者完善相关临床检查,比较两组的血清LpPLA2水平和微栓子信号阳性率。结果DACI组的血清LpPLA2水平为(442.2±67.4)μg/L,高于NDACI组的(324.1±54.9)μg/L,差异有统计学意义(P<0.05)。DACI组的微栓子信号阳性率为92.00%,高于NDACI组的68.57%(P<0.05)。结论急性脑梗死合并2型糖尿病患者的血清LpPLA2水平及微栓子信号阳性率均较高,表明血清LpPLA2与微栓子信号阳性是引起急性脑梗死合并2型糖尿病的危险因素。
Objective To explore the correlation between microemboli and serum 1 ipoprotein-associated phospholipase A2(LpPLA2)in patients with acute cerebral infarction complicated with type 2 diabetes mellitus.Methods 120 cases of patients with acute cerebral infarction admitted to our hospital from September 2017 to May 2019 were selected and divided into DACI group(with type 2 diabetes mellitus,50 cases)and NDACI group(without type 2 diabetes mellitus,70 cases)according to whether patients had diabetes mellitus.All patients completed the related clinical examinations,and the serum LpPLA2 level and the positive rate of microemboli signals were compared between the two groups.Results The serum LpPLA2 level of DACI group was(442.2±67.4)μg/L,higher than(324.1±54.9)μg/L of NDACI group(P<0.05).The positive rate of microemboli signals in DACI group was 92.00%,higher than 68.57%in NDACI group(P<0.05).Conclusions Serum LpPLA2 and the positive rate of microemboli signals are higher in patients with acute cerebral infarction complicated with type 2 diabetes mellitus,suggesting that serum LpPLA2 and microemboli signals are the risk factors of acute cerebral infarction complicated with type 2 diabetes mellitus.
作者
贺文麟
王科
李云桥
HE Wenlin;WANG Ke;LI Yunqiao(Department of Neurology,Huizhou Third People's Hospital,Huizhou 516002,China)
出处
《临床医学工程》
2020年第1期33-34,共2页
Clinical Medicine & Engineering
基金
惠州市科技计划项目(项目编号:2018Y170)
关键词
急性脑梗死
2型糖尿病
微栓子
血清脂蛋白相关磷脂酶A2
Acute cerebral infarction
Type 2 diabetes mellitus
Microemboli
Serum lipoprotein-associated phospholipase A2
