摘要
目的:初步探讨卵巢移位术的最佳移位点,为卵巢在宫颈癌盆腔放疗中的防护提供更多的理论依据。方法:在Elekta Xio计划系统中,分别对仿真体模和宫颈癌患者模拟四野均等、四野非均等、前后两野对穿、左右两野对穿等照射,评估各位点的吸收剂量。结果:各位点的吸收剂量随着卵巢移位高度的增加而显著降低(P<0.01),髂嵴上3cm层面各位点的吸收剂量为(2.94±1.12)Gy,略小于3Gy(P>0.05),髂嵴上4.5cm以上层面各位点的吸收剂量为(1.70±0.22)Gy,明显小于3Gy(P<0.01)。并且两个高度层面的侧方位点的剂量均低于后方。结论:对于接受盆腔盒式放疗的宫颈癌患者,建议在允许范围内将卵巢至少移至髂嵴上3~4.5cm层面,并固定于结肠旁沟靠近侧方的区域,以此减少移位卵巢的吸收剂量。
Objective:To initially explore the optimal transposed site of ovarian transposition,and provide more theoreti-cal basis for ovarian protection in pelvic radiotherapy for cervical cancer.Methods:In the Elekta Xio treatment planning sys-tem,equal four-field irradiation,unequal four-field irradiation and two parallel opposed fields irradiation were simulated for humanoid phantoms and cervical cancer patients.The absorbed dose at each point was assessed.Results:As the height of o-varian movement increased,the dose in each site decreased significantly(P<0.01).The absorbed dose of each point on the layer 3cm above the iliac crest was(2.94±1.12)Gy,slightly less than 3Gy(P>0.05),and the absorbed dose of each point on the layer 4.5cm above the iliac crest was(1.70±0.22)Gy which was significantly less than 3Gy(P<0.01).Simultaneous-ly,the dose in side of the two layers was less than that in the rear of these two layers.Conclusion:For cervical cancer pa-tients undergoing pelvic radiotherapy,it is recommended to transpose the ovary to at least 3-4.5 cm above the iliac crest and fix it to the area near the side of paracolic sillcus,thus reducing the transposed ovarian dose.
作者
胡明宗
周本梅
贾钰铭
雷开键
徐国洪
Hu Mingzong;Zhou Benmei;Jia Yuming;Lei Kaijian;Xu Guohong(Department of Radiotherapy,The Second People’s Hospital of Yibin,Yibin 644000,Sichuan,China;Department of Oncology,The Second People’s Hospital of Yibin,Yibin 644000,Sichuan,China)
出处
《肿瘤预防与治疗》
2020年第1期28-32,共5页
Journal of Cancer Control And Treatment
基金
宜宾市科技计划项目(编号:2014SF019)~~
关键词
宫颈癌
卵巢移位术
盆腔放疗
吸收剂量
Cervical cancer
Ovarian transposition
Pelvic radiotherapy
Absorbed dose
