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观察输注去氧肾上腺素对布比卡因蛛网膜下腔阻滞麻醉剖宫产效果的影响

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摘要 目的:观察采用不同静脉滴速的去氧肾上腺素对布比卡因蛛网膜下腔阻滞麻醉剖宫产效果的影响以及不良反应情况。方法:选取2018年3月1日至2019年3月1日期间在我院妇产科行剖宫产手术产妇225例作为研究对象,随机分为不同静脉滴速的去氧肾上腺素A组、B组和C组各75例。统计三组产妇的一般资料、手术相关资料以及不良反应情况。结果:三组产妇的年龄、BMI、孕周、手术时间、麻醉风险分级比较,差异无统计学意义(p>0.05)。B组和C组有效麻醉率、起效时间、维持时间比较差异无统计学意义(84.0% vs 93.3%,5.1±1.8min vs 4.9±1.2min,60.5±4.8min vs 63.6±5.2minP>0.05);B组和C组有效麻醉率、维持时间均高于和起效时间均低于A组差异有统计学意义(84.0%、93.3% vs 66.7%,60.5±4.8min、63.6±5.2min vs 57.3±3.1min,5.1±1.8min、4.9±1.2min vs 7.5±2.1min P<0.05)。三组发生寒战、心动过缓的不良反应率比较差异无统计学意义(P>0.05);A组和B组发生低血压、恶心、呕吐不良反应率比较差异无统计学意义(5.3% vs 6.7%,8.0% vs 10.7%,6.7% vs 9.3% P>0.05);A组和B组发生低血压、恶心、呕吐不良反应率低于C组,差异有统计学意义(5.3%、6.7% vs 17.3%,8.0%、10.7% vs 24.0%,6.7%、9.3% vs 25.3% P>0.05)。结论:在去氧肾上腺素(100μg/ml)40μg/min、30μg/min、20μg/min三种不同的静脉输注速度中,30μg/min静脉输注速度能够明显降低布比卡因蛛网膜下腔阻滞麻醉中产生低血压、恶心、呕吐的不良反应率和减少对麻醉效果的影响。
作者 王庆利
出处 《黑龙江中医药》 2019年第6期193-194,共2页 Heilongjiang Journal of Traditional Chinese Medicine
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  • 1CHEN Xin-zhong CHEN Hong LOU Ai-fei, Lü Chang-cheng.Dose-response study of spinal hyperbaric ropivacaine for cesarean section[J].Journal of Zhejiang University-Science B(Biomedicine & Biotechnology),2006,7(12):992-997. 被引量:21
  • 2Williamson W,Burks D,Pipkin J.Effect of timing of fluid bolus onreduction of spinal-Induced hypotension in patients undergoing electivecesarean delivery[J].AANA Journal,2009(2):130-136.
  • 3Tamilselvan P,Femando R,Bray J.The Effects of crystalloid and colloidpreload on cardiac output in the parturient undergoing planned cesareandelivery under spinal anesthesia:a randomized trial[J].Anesthesia andAnalgesia,2009(6):1916-1921.
  • 4ARZOLA C, WIECZOREK P M. Efficacy of low - dose bupivacaine in spinal anaesthesia for Caesarean delivery: systematic review and meta - analysis [ J ]. British Journal of Anaesthesia, 2011, 107(3) : 308 -318.
  • 5NGAN KEE W D, LEE Anna, KHAW K S, et al. A randomized double - blinded comparison of phenylephrine and ephedrine infusion combinations to maintain blood pressure during spinal anesthesia for cesarean delivery: the effects on fetal acid - base status and hemodynamic control [ J ]. Anesthesia and Analgesia, 2008, 107(4) : 1295 -1302.
  • 6COOPER D W, CARPENTER M, MOWBRAY P, et al. Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery [ J ]. Anesthesiology, 2002, 97 (6) : 1582 -1590.
  • 7NGAN KEE W D, KHAW K S, TAN P E, et al. Placental transfer and fetal metabolic effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery [ J ]. Anesthesiology, 2009, 111(3) : 506 -512.
  • 8VAN DE VELDE M, VAN SCHOUBROECK D, JANI J, et al. Combined spinal - epidural anesthesia for cesarean delivery : dose - dependent effects of hyperbaric bupivacaine on maternal hemodynamics[J]. Anesthesia and Analgesia, 2006, 103 ( 1 ) : 187 - 190.
  • 9LEWINSKY R M, RISKIN - MASHIAH S. Autonomic imbalance in preeclampsia: evidence for increased sympathetic tone in response to the supine -pressor test [ J ]. Obstetrics and Gynecology, 1998, 91 (6): 935-939.
  • 10Cluver C, Novikova N, Hofmeyr GJ, et al. Maternal position during caesarean section for preventing maternal and neonatal complications [ J ]. Cochrane Database Syst Rev, 2013,3 : CD007623.

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