摘要
目的对比研究动脉栓塞术(TAE)与微波消融治疗肝海绵状血管瘤(CHL)患者的临床疗效。方法2014年1月~2018年4月我院综合介入科就诊的74例CHL患者,其中37例接受微波消融治疗,另37例接受TAE治疗,随访6个月。结果两组疗效比较,无统计学差异(86.5%对75.7%,P>0.05);治疗后,微波消融组血清丙氨酸氨基转移酶和天门冬氨酸氨基转移酶水平分别为(47.9±5.7)U/L和(35.5±4.3)U/L,显著低于TAE组[分别为(93.5±11.2)U/L和(61.3±5.8)U/L,P<0.05];术后12 h、24 h和48 h时,微波消融组视觉模拟评分分别为(2.8±0.5)分、(1.7±0.2)分和(1.1±0.1)分,显著低于TAE组[分别为(4.7±0.9)分、(2.6±0.8)分和(1.8±0.3)分,P<0.05];治疗后,两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论TAE和微波消融治疗CHL患者疗效类似,术后不良反应发生率低,临床可根据技术条件选择应用。
Objective The aim of this study was to compare the clinical efficacy of transcatheter arterial embolization(TAE)and microwave ablation in the treatment of patients with cavernous hemangioma of liver(CHL).Methods 74 patients with CHL were recruited in the Department of General Intervention between January 2014 and April 2018,and 37 were treated by microwave ablation and another 37 were treated by TAE.All patients were followed-up for six months.Results There was no statistical difference as respect to the clinical efficacy between the two groups(86.5%vs.75.7%,P>0.05);After treatment,serum levels of alanine aminotransferase and aspartate aminotransferase in microwave ablation group were(47.9±5.7)U/L and(35.5±4.3)U/L,significantly lower than[(93.5±11.2)U/L and(61.3±5.8)U/L,P<0.05]in the TAE group;at 12 h,24 h and 48 h after operation,the visual analogue score in the microwave ablation group were(2.8±0.5),(1.7±0.2)and(1.1±0.1),significantly lower than[(4.7±0.9),(2.6±0.8)and(1.8±0.3),respectively,P<0.05]in the TAE group;After treatment,there was no significant difference in the incidence of adverse reactions between the microwave ablation and the TAE-treated group(P>0.05).Conclusion The application of TAE and microwave ablation in the treatment of patients is efficacious,which has little side effects and lower incidence of postoperative pain.
作者
李陆鹏
曹广劭
曹会存
刘建文
刘玉岩
Li Lupeng;Cao Guangshao;Cao Huicun(Department of General Intervention,Provincial People's Hospital,Zhengzhou 450000,Henan Province,China)
出处
《实用肝脏病杂志》
CAS
2020年第2期276-279,共4页
Journal of Practical Hepatology
基金
河南省医学科技公关计划项目(编号:2018020392)
关键词
肝海绵状血管瘤
动脉栓塞术
微波消融
视觉模拟评分
疗效
Cavernous hemangioma of liver
Transcatheter arterial embolization
Microwave ablation
Efficacy
