摘要
目的:观察腹腔镜阑尾切除术(LA)与开放阑尾切除术(OA)对阑尾炎合并高血压患者血管内皮素(ET)与C反应蛋白(CRP)的影响。方法:将2018年4月至2019年4月就诊的120例阑尾炎合并高血压患者分为两组,每组60例,分别行OA与LA。分别于术前、术中、术后12 h、术后24 h取静脉血,检测血液中ET、CRP水平。结果:术前,两组患者ET、CRP水平差异无统计学意义(P>0.05);术中、术后12 h、术后24 h,OA组ET、CRP水平高于LA组,差异有统计学意义(P<0.05)。结论:LA、OA均对患者ET、CRP有明显影响,但OA较LA更明显,可见腹腔镜手术对机体刺激较小,对阑尾炎合并高血压患者更为安全。
Objective:To investigate the effects of open appendectomy(OA) and laparoscopic appendectomy(LA) on the level of endothelin(ET) and C-reactive protein(CRP) in patients with hypertension.Methods:From Apr.2018 to Apr.2019,120 patients with appendicitis and hypertension were included in the study and divided into two groups.One group received OA(n=60),the other received LA(n=60).Venous blood was drawn before the operation,during the operation,as well as 12 and 24 h after the operation in order to analyze the levels of ET and CRP.Results:The levels of ET and CRP of two groups were not statistically significantly different before the operation(P>0.05).The level of ET and CRP in the OA group were significantly higher than those in the LA group during the operation as well as 12 and 24 h after the operation.Conclusions:Both OA and LA have significant effects on the level of ET and CRP of patients,which were more obvious in the OA. LA seems to have less stimulation to the body and is safer for patients with appendicitis and hypertension.
作者
胡慧
弓小雪
HU Hui;GONG Xiao-xue(The First People's Hospital of Jining,Jining 272000,China)
出处
《腹腔镜外科杂志》
2020年第2期138-140,共3页
Journal of Laparoscopic Surgery
基金
山东省保健科技协会科学技术课题(SDBJKT20180099)
