摘要
目的分析淄博市2015-2018年肾综合征出血热(hemorrhagic fever with renal syndrome,HFRS)的流行特征、宿主分布及其携带病毒的情况,为防控工作提供依据。方法运用描述性流行病学方法对全市疫情资料和宿主动物监测数据进行统计分析。结果 2015-2018年全市报告肾综合征出血热315例,死亡1例,平均发病率为1.69/10万,病死率0.32%。病例主要集中在淄川区和沂源县,占全市总病例数的67.62%。以中老年农民为主,45~69岁年龄组占总病例数的62.86%。发病时间主要集中在3-5月和10-12月。全市平均鼠密度为3.04%,鼠带病毒率为3.87%,居民区以褐家鼠为优势鼠种,野外以黑线姬鼠为优势鼠种,褐家鼠和黑线姬鼠带毒率分别为6.48%和0.75%,两种鼠带毒率差异有统计学意义(χ~2=6.694,P=0.01)。结论淄博市HFRS发病呈下降趋势,但疫情高发区(县)的鼠密度和鼠带病毒率维持在较高水平,存在HFRS爆发流行的风险,应继续加强重点地区的疫苗接种,落实防鼠灭鼠及健康教育等综合措施。
Objective To analyze the epidemic characteristics of hemorrhagic fever with renal syndrome(HFRS),the distribution and virus-carrying status of host animals in Zibo City from 2015 to 2018,so as to provide references for prevention and control.Methods Descriptive epidemiological study was conducted on the incidence data of HFRS collected in Zibo City from 2015 to 2018.Results A total of 315 cases including one death were reported in Zibo,with the average incidence of 1.69/100000 and the fatality rate of 0.32%.The cases were distributed mainly in Zichuan District and Yiyuan Coutry,which accounting for 67.62%.The main groups of cases were middle-aged and elderly farmers,and people aged 45-69 accounted for 62.86%of total cases.Two peak seasons were observed in spring(March-May)and autumn-winter(October-December).The average rat density and virus-carrying rate were 3.04%and 3.87%respectively rattus norvegicus was the dominant species of rodents in the residential area,while in the field,apodemus agrarius was the dominant species.The virus-carrying rates of rattus norvegicus and apodemus agrarius were 6.48%and 0.75%respectively,which had significant difference in these two group(χ~2=6.694,P=0.01).Conclusions The incidence rate of HFRS was declining in Zibo City,while the rat density and the virus-carrying rate were still high in the areas with high incidence,which indicating the outbreak risk of HFRS was existed.It is necessary to strengthen immunization,rodent control and health education in high-endemic areas.
作者
王玲
张艳
张玲
刘芳盈
孙涛
姜晓林
王志强
王显军
WANG Ling;ZHANG Yan;ZHANG Ling;LIU Fang-ying;SUN Tao;JIANG Xiao-lin;WANG Zhi-qiang;WANG Xian-jun(Center for Disease Control and Prevention,Shandong Center for Disease Control and Prevention,Jinan 250014,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2020年第2期237-240,共4页
Chinese Journal of Disease Control & Prevention
基金
国家科技重大专项(2017ZX10104001-005-001)。
关键词
肾综合征出血热
流行特征
监测
Hemorrhagic fever with renal syndrome
Epidemic characteristics
Monitor
