摘要
目的考察传统膏方的长期稳定性,为膏方的质量标准研究工作提供实验依据。方法以具有传统中医特色的益母阿胶膏为模型药物,在常规传统膏方的储存条件下(陶瓷容器密封包装、冰箱2~8℃条件下储存),分别考察其在0、1、2、3、6、12个月的水分含量、相对密度及微生物限度。结果在12个月内,益母阿胶膏的微生物限度、水分含量和相对密度均符合《中国药典》(2015年版)的有关规定。结论采用传统方法制作的膏方,常规膏方的储存条件下,在12个月内质量稳定。
Objective To investigate the long-term stability of the traditional cream formula and provide experimental basis for the quality standard research of the cream formula.Methods Yimu E-jiao ointment with traditional Chinese medicine characteristics was taken as the model drug,the water content,relative density and microbial limit of Yimu E-jiao ointment in 0,1,2,3,6,12 months were investigated under the storage conditions of conventional traditional ointment(sealed packaging with ceramic container,stored in refrigerator under 2-8℃).Results Within 12 months,the microbial limit,water content and relative density of Yimu E-jiao cream were in line with the relevant regulations of Chinese Pharmacopoeia(2015 Edition).Conclusion The quality of the traditional cream is stable within 12 months using conventional fabricated methods under the routine storage conditions.
作者
梁欣健
姜倩娥
孔燕兴
王叶茗
周健文
LIANG Xinjian;JIANG Qian'e;KONG Yanxing;WANG Yeming;ZHOU Jianwen(Guangzhou Hospital of Integrated Traditional Chinese and Western Medicine,Guangzhou 510801,China;Tianhe District Hospital of Traditional Chinese Medicine,Guangzhou 510665,China;Guangdong Zaitian Pharmaceutical Co.,Ltd.,Qingyuan 511517,China)
出处
《中国医药科学》
2020年第3期42-45,共4页
China Medicine And Pharmacy
关键词
膏方
长期稳定性
微生物限度
水分
相对密度
Cream formula
Long-term stability
Microbial limit
Water content
Relative density
