摘要
目的探究小儿支气管肺发育不良合并不同程度肺动脉高压(PH)的临床特征及预后效果。方法选取上海市第一人民医院宝山分院2017年12月-2018年12月支气管肺发育不良合并不同程度PH患儿68例为研究对象。对检测结果进行回顾性分析。其中支气管肺发育不良并轻度PH患儿30例(轻度组),中度PH患儿26例(中度组),重度PH患儿12例(重度组)。对所有患儿进行肺动脉压力监测,比较患儿临床特征及预后情况。结果中度组与重度组的患儿出生时体重、胎龄和Apgar评分显著低于轻度组,吸氧时间显著长于轻度组;中度组、重度组患儿的PVRI、mPAP值显著高于轻度组,PAWP值显著低于轻度组;中度组、重度组患儿预后不良事件发生率显著高于轻度组,重度组患儿预后不良事件发生率显著高于中度组,上述数据差异均有统计学意义(P<0.05)。结论小儿支气管肺发育不良合并重度PH患儿多表现为出生时体重低、胎龄短、肺动脉压力较高和预后效果较差。
OBJECTIVE To explore the clinical features and prognostic effects of bronchopulmonary dysplasia with pulmonary hypertension(PH)of different degrees in children. METHODS 68 cases children with bronchopulmonary dysplasia and PH of different degrees who were treated in target hospital from December 2017 to December 2018 were selected as the study subjects. According to the test results, 30 children with bronchopulmonary dysplasia complicated with mild PH(mild group),26 children with moderate PH(moderate group),and 12 cases children with severe PH(severe group)were analyzed retrospectively. Pulmonary arterial pressure monitoring was performed in all children to compare the clinical features and prognosis of the children. RESULTS The weight, gestational age, and Apgar scores of the children in the moderate and severe groups were significantly lower than those in the mild group, and the oxygen inhalation time was significantly longer than that in the mild group;the PVRI and mPAP values in the moderate and severe groups were significantly higher than those in the moderate and severe groups, and the PAWP value was significantly lower than the mild group;the incidence of adverse prognosis in the moderate group and the severe group was significantly higher than the mild group,and the incidence of prognosis in the severe group was significantly higher than in the moderate group, the above data were statistically significant(P<0.05).CONCLUSION Children with bronchopulmonary dysplasia combined with severe PH were characterized by low body weight,short gestational age, high pulmonary artery pressure and poor prognosis.
作者
宋云华
陈继源
谭金童
张昱
王茂壮
张芳
SONG Yun-hua;CHEN Ji-yuan;TAN Jin-tong(Baoshan Branch of Shanghai First People’s Hospital,Shanghai,200940,China)
出处
《中国初级卫生保健》
2020年第1期109-111,共3页
Chinese Primary Health Care
关键词
支气管肺发育不良
肺动脉高压
早产儿
右心导管
临床特征
预后
bronchopulmonary dysplasia
pulmonary hypertension
premature infant
right cardiac catheterization
clinical featuresr
prognosis
