摘要
脑肠轴是肠神经系统和中枢神经系统之间的双向信息交流通路,肠道功能障碍可增加神经退行性疾病、神经精神疾病等中枢神经系统疾病的患病风险,改善肠道功能可减轻中枢神经系统疾病的症状,但其调控机制仍不明确。本文围绕脑肠轴中肠道对脑功能的调节机制综述如下。
The gut brain axis consists of bidirectional'routes of communication between the enteric nervous system and the central nervous system.Intestinal dysfunction can increase the risk of neurodegenerative disease,neuropsychiatric disease and other central system diseases.Improving intestinal function could alleviate symptoms of central system diseases,while the mechanism of that is still unclear.This article reviews the mechanism of intestinal regulation on brain in the gut brain axis.
作者
苗继文
程波
李娜
李岩松
王强
李爽
Miao Jiwen;Cheng Bo;Li Na;Li Yansong;Wang Qiang;Li Shuang(Department of Anesthesiology,First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2020年第4期422-426,共5页
Chinese Journal of Neuromedicine
基金
陕西省自然科学基金(2017JM8048)。
关键词
脑肠轴
迷走神经
肠神经系统
肠道微生物
Gut brain axis
Vagus nerve
Enteric nervous system
Intestinal microorganism
