摘要
紫杉醇诱发神经病理性疼痛的治疗一直是研究的热点,且其在靶向治疗领域已经取得了一些进展。文章介绍了参与紫杉醇诱发神经病理性疼痛的受体或通路,神经病理性疼痛的特点,紫杉醇诱发神经病理性疼痛的靶向治疗方法的总结以及其他治疗方法的研究进展等内容。通过对紫杉醇诱发神经病理性疼痛的靶向治疗方法的总结,研究和展望未来其他可能的治疗方法,深入探索紫杉醇诱发神经病理性疼痛的有效治疗方法,进一步为临床上的治疗提供可能的依据。
The treatment of paclitaxel-induced neuropathic pain has been a research hotspot.Also,some progress has been made in the field of targeted therapy.In this article,we introduced paclitaxel,summarized the receptors or pathways that involved in pa-clitaxel-induced neuropathic pain,the characteristics of neuropathic pain that induced by paclitaxel,targeted treatment methods of pa-clitaxel-induced neuropathic pain and the progress of other treatment methods.By reviewing the targeted treatment methods of paclitax-el-induced neuropathic pain,we proposed and predicted other possible treatment methods in the future,explored the effective treatment methods of paclitaxel-induced neuropathic pain and provided possible basis for clinical treatment.
作者
缑泽鹏
王秀丽
Gou Zepeng;Wang Xiuli(Department of Anesthesiology,the Third Hospital of Hebei Medical University,Shijiazhuang 050051,China)
出处
《国际麻醉学与复苏杂志》
CAS
2020年第3期305-310,共6页
International Journal of Anesthesiology and Resuscitation
基金
河北省自然科学基金(H2018206260)。
