摘要
目的分析粤北地区2019年男性精液质量情况,为临床诊疗提供参考依据。方法4505例进行精液常规检查的男性患者作为研究对象,依据患者年龄分为A组(年龄≤30岁,2158例)、B组(年龄31~39岁,1896例)、C组(年龄40~50岁,406例)、D组(年龄>50岁,45例)。分析精液常规检验结果,比较四组患者精液常规检测结果[精液pH值、精液量、精子浓度、精子活动率、向前运动精子(PR)参数、精子正常形态率、精子总数]及精液参数(精液量、精液pH值、精子浓度、精子总数、精子活动率、前向运动精子、精子形态)异常发生率。结果4505例男性患者中,精液各项指标均正常患者占16.1%(725/4505),精液质量异常患者占83.9%(3780/4505),无精子症患者占1.7%(78/4505)。各项精液参数的异常发生率排名前三的分别为:精子形态异常(78.6%,3541/4505)、向前运动精子百分率(23.7%,1067/4505)、精子活动率(14.7%,663/4505)。四组精液p H值比较差异无统计学意义(P>0.05);B组精子浓度与C组比较差异无统计学意义(P>0.05),与A组和D组比较差异有统计学意义(P<0.05);四组精液量、精子活动率、向前运动精子、精子正常形态率和精子总数随着年龄的增加均呈现下降趋势,差异有统计学意义(P<0.05);其中D组与A、B、C组比较差异有统计学意义(P<0.05)。精子参数异常发生率随着患者年龄增长呈现出显著升高的趋势。D组精液量、精液pH值、精子活动率、向前运动精子及精子浓度、精子总数、精子形态异常发生率与A、B、C组比较差异有统计学意义(P<0.05)。结论粤北地区2019年男性患者的精液质量与年龄呈现负相关关系,影响本地区男性生育能力的精液因素主要为精子形态和精子活动力异常。
Objective To analyze the male semen quality in northern Guangdong in 2019,so as to provide reference for clinical diagnosis and treatment.Methods A total of 4505 male patients with semen routine test as study subjects were divided into group A(age≤30 years old,2158 cases),group B(age 31-39 years old,1896 cases),group C(age 40-50 years old,406 cases)and group D(age>50 years old,45 cases).The semen routine test results was analyzed.The semen routine test results[semen pH value,semen volume,sperm concentration,sperm motility,forward moving sperm(PR)parameters,normal sperm morphology rate,total sperm count],abnormal rate of semen parameters(semen volume,semen pH value,sperm concentration,total sperm count,sperm activity rate,forward moving sperm,sperm morphology)were compared among four groups.Results Among 4505 male patients,16.1%patients(725/4505)had normal semen parameters;83.9%(3780/4505)patients had abnormal semen quality;and 1.7%patients(78/4505)had azoospermia.The top three abnormal rates of semen parameters were:abnormal sperm morphology(78.6%,3541/4505),forward moving sperm percentage(23.7%,1067/4505),sperm activity rate(14.7%,663/4505).There was no statistically significant difference in semen pH value among the four groups(P>0.05).There was no statistically significant difference in sperm concentration between group B and group C(P>0.05),and there was statistically significant difference between group A and group D(P<0.05).The semen quantity,sperm activity rate,forward movement sperm parameters,normal sperm morphology rate and total sperm number decreased with the increase of age in the four groups,and the difference was statistically significant(P<0.05).The difference between group D and group A,B and C was statistically significant(P<0.05).The incidence of abnormal sperm parameters increased with the age of patients.There were statistically significant difference in semen volume,semen pH value,sperm motility,forward movement sperm and sperm concentration,total sperm count,and abnormal rate of semen morphology in group D compared with groups A,B,and C(P<0.05).Conclusion The age of male patients in northern Guangdong has a negative correlation with their semen quality.The semen factors that affect male fertility in this area are mainly abnormal sperm morphology and sperm motility.
作者
汪成
范舒舒
张思
黄文波
侯志伟
罗慧旗
WANG Cheng;FAN Shu-shu;ZHANG Si(Reproductive Center of Yuebei People’s Hospital,Shaoguan 512025,China)
出处
《中国现代药物应用》
2020年第8期30-32,共3页
Chinese Journal of Modern Drug Application
基金
韶关市卫生计生科研项目(项目编号:Y18027)。
