摘要
目的探究活血续断汤治疗闭合性骨折的效果、分析影响疗效的因素以及干预策略。方法选取2016年5月~2018年1月在北京市昌平区中医医院接受治疗的闭合性骨折的患者83例纳入观察对象,按照随机数字表法将其分为对照组(41例)与实验组(42例)。对照组采用闭合复位配合夹板外固定、给予常规抗生素、护骨胶囊等常规疗法;实验组在对照组的基础上增加自拟活血续断汤治疗。观察两组患者治疗后的临床疗效、炎性因子、疼痛、肿胀程度。采用logistic回归检验实验组治疗效果的影响因素。结果实验组总有效率高于对照组,差异有统计学意义(P <0.05);治疗后实验组的白细胞介素-6、白细胞介素-8水平明显低于对照组,差异均有统计学意义(均P <0.05)。治疗1 d后两组患者患处疼痛评分和肿胀程度评分比较,差异无统计学意义(P> 0.05);治疗7 d后两组患者的患处疼痛评分和肿胀程度评分较治疗1 d后降低,且实验组明显低于对照组,差异均有统计学意义(均P <0.05)。实验组治疗无效的原因与性别、年龄、致伤原因无相关性(P> 0.05),与患者睡眠时间以及其是否食用生冷酸辣食物有相关性(P <0.05)。logistic回归分析显示:睡眠时间<8 h和经常食用生冷酸辣食物是造成治疗无效的危险因素(P <0.05)。结论自拟活血续断汤治疗闭合性骨折的效果较好,临床上值得推广应用。在使用该法治疗时,患者应当谨遵医嘱、严格控制饮食,并且有足够的睡眠时间。
Objective To explore the effect of Huoxue Xiuduan Decoction in the treatment of closed fractures,analyze the factors influencing the curative effect and the intervention strategies.Methods A total of 83 patients with closed fractures who were treated in Beijing Changping Hospital of Traditional Chinese Medicine from May 2016 to January2018 were selected for observation and divided into the control group(41 cases)and the experimental group(42 cases)according to the random number table method.The control group was treated with conventional therapies such as closed reduction combined with splint external fixation,conventional antibiotics and bone protecting capsules.On the basis of the control group,the experimental group was treated with self-designed Huoxue Xiuduan Decoction.The clinical efficacy,inflammatory factors,pain and swelling degree of the two groups were observed.Logistic regression was used to test the influencing factors of the treatment effect of the experimental group.Results The total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of interleukin-6 and interleukin-8 in the experimental group were significantly lower than those in the control group,with statistically significant differences(all P<0.05).After 1 day of treatment,there was no statistically significant difference between the two groups in pain score and swelling degree score(P>0.05).After 7days of treatment,the pain and swelling degree scores of the two groups were lower than those after 1 day of treatment,and the experimental group was significantly lower than the control group,with statistically significant differences(all P<0.05).The reasons for the ineffective treatment in the experimental group were not correlated with gender,age,and cause of injury(P>0.05),and were correlated with the patients′sleep time and whether they ate raw,cold,sour and spicy food(P < 0.05). Logistic regression analysis showed that sleep time < 8 h and frequent consumption of cold, sour and spicy food were risk factors for treatment failure(P<0.05).Conclusion The effect of self-designed Huoxue Xiuduan Decoction in the treatment of closed fracture is good,and it is worth popularizing in clinic.When using this treatment,the patient should follow the doctor’s advice,follow a strict diet,and get enough sleep.
作者
朱康
王晓桐
马胡晶
杜海山
ZHU Kang;WANG Xiaotong;MA Hujing;DU Haishan(Department of Orthopedics,Beijing Changping Hospital of Traditional Chinese Medicine,Beijing 102200,China)
出处
《中国医药导报》
CAS
2020年第12期93-96,共4页
China Medical Herald
