摘要
川崎病是一种系统性血管炎,最严重的并发症是冠状动脉扩张和冠状动脉瘤,其主要治疗主要包括大剂量丙种球蛋白静滴及口服阿司匹林,而在葡萄糖-6-磷酸脱氢酶(glucose-6-phosphate dehydrogenase,G6PD)缺乏症通常被认为是阿司匹林摄入的相对禁忌证。本病例报道了川崎病合并G6PD缺乏症患儿心脏彩色超声提示冠状动脉瘤形成,大剂量丙种球蛋白静脉滴注后,加用小剂量阿司匹林抗血小板聚集,得到成功诊治的诊治过程,并对相关文献进行了复习,以期引起临床医生的重视,为临床工作提供借鉴。
Kawasaki disease is a systemic vasculitis.The most serious complications are coronary artery dilatation and coronary artery aneurysm.The main treatments include high-dose gamma globulin intravenous drip and oral aspirin.G6PD deficiency is usually considered a relative contraindication of aspirin intake.In this paper,we reported that the color Doppler ultrasound of children with Kawasaki disease complicated with G6PD deficiency showed coronary aneurysm formation.After high-dose gamma globulin intravenous drip,plus low-dose aspirin for preventing platelet aggregation,a successful diagnosis and treatment process was obtained.And the relevant literature was reviewed to arouse the attention of clinicians and to provide reference for clinical work.
作者
施惠宣
陈国兵
陈先睿
Shi Huixuan;Chen Guobing;Chen Xianrui(Department of Pediatrics, the First Affiliated Hospital of Xiamen University, Pediatric Key Laboratory of Xiamen, Institute of Pediatrics, School of Medicine,Xiamen University, Xiamen 361003, China)
出处
《临床荟萃》
CAS
2020年第6期555-557,共3页
Clinical Focus
