摘要
目的 检测老年性阴道炎患者免疫功能,探讨影响患者预后的相关因素.方法 选取2018年11月至2019年11月我院收治的102例老年性阴道炎患者作为研究对象,并根据临床治疗效果将其分为预后良好组和预后不良组.收集2组患者的一般资料,观察2组局部免疫指标水平和阴道健康状况,并利用χ2检验与多因素Logistic回归分析法对影响老年性阴道炎患者预后的相关因素进行分析.结果 102例患者中,预后良好80例;预后不良22例.与预后良好组比较,预后不良组的白细胞介素-1β(IL-1β)水平、阴道pH值均明显升高(P<0.05),免疫球蛋白A(sIgA)水平及阴道健康状况评分、阴道炎症评分均明显降低(P<0.05).多因素Logistic回归分析示:sIgA、IL-1β、阴道pH值、阴道炎症评分、阴道健康评分、内裤混洗、清洗外阴方式、盆腔炎史均是影响老年性阴道炎患者预后不良的独立危险因素(P<0.05).结论 老年性阴道炎的治疗不能仅依赖于药物,应在药物治疗的基础上给予积极的营养支持和健康知识教育,以此提高患者的免疫功能,改善患者预后.
Objective To detect the immune function of the senile vaginitis,and to explore the related factors that affect the prognosis of the patients.Methods One hundred and two cases of senile vaginitis treated in our hospital from November 2018 to November 2019 were selected as the subjects of the study,and they were divided into the group with good prognosis and poor prognosis according to the clinical treatment effect.The general data of the two groups were collected to observe the level of local immune indexes and vaginal health,χ2 test and multivariate Logistic regression analysis were used to analyze the related factors affecting the prognosis of senile vaginitis patients.Results Among the 102 patients,the prognosis was good in 80 cases,and the prognosis was poor in 22 cases.Compared with the good prognosis group,the level of IL-1β,vaginal pH value in the poor prognosis group were significantly higher than those in the good prognosis group,while the immunoglobulin A(sIgA)level and vaginal health status score and vaginal inflammation score were significantly decreased(P<0.05).Multivariate logistic regression analysis showed that sIgA,IL-1β,vaginal PH,vaginal inflammation score,vaginal health score,underpants mixed washing,cleaning vulva style,and history of pelvic inflammation were independent risk factors for poor prognosis in patients with senile vagini-tis(P<0.05).Conclusion The treatment of senile vaginitis can not only rely on drugs,but should be given active nutritional support and health knowledge education on the basis of drug treatment,so as to improve the immune function of patients and improve the prognosis of patients.
作者
李瑞琴
马欢
刘婉
Li Ruiqin;Ma Huan;Liu Wan(Department of Obstetrics and Gynaecology,First Hospital of Yulin City,Shaanxi 718000,China)
出处
《山西医药杂志》
CAS
2020年第10期1217-1219,共3页
Shanxi Medical Journal
