摘要
目的:观察自拟湿热型盆腔炎方联合介入术治疗对输卵管性不孕(湿热瘀阻型)患者妊娠率的影响。方法:选择2017年6月~2018年6月我院收治的输卵管性不孕(湿热瘀阻型)患者80例,按随机数表法分为观察组与对照组,各40例。对照组于月经干净后4~7天由介入科行输卵管介入术治疗,术后第2天口服妇可靖胶囊,观察组同样行输卵管介入术治疗,术后第2天应服用自拟湿热型盆腔炎方。比较两组治疗后的输卵管再通率、中医证候积分、血清炎性因子水平[白细胞介素-2(IL-2)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]。随访1年,记录两组妊娠率及并发症发生率。结果:两组输卵管再通率比较,差异无统计学意义(P>0.05);治疗后观察组中医症候积分显著低于对照组,IL-2水平显著高于对照组,IL-6、TNF-α水平显著低于对照组,差异有统计学意义(P<0.05);观察组宫内妊娠率显著高于对照组,并发症发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:采用自拟湿热型盆腔炎方联合介入术治疗输卵管性不孕(湿热瘀阻型),可快速缓解患者不适症状,促进输卵管再通,有效提高妊娠率,或与减轻炎性损伤,促进炎症吸收,调节机体免疫有关。
Objective:To explore the effect of Self-made Damp-heat Type Pelvic Inflammation Recipe combined with inter-ventional therapy on pregnancy rate for patients with tubal infertility(damp-heat stagnation type).Methods:Eighty patients with tubal infertility(damp-heat stagnation type)admitted to our hospital from June 2017to June 2018were selected and divided into observation group and controlled group according to the random number table method,with 40cases in each group.The controlled group was treated with tubal intervention in intervention department at 4th to 7th day after menstruation cleansing and given oral ad-ministration of Fukejing Capsule on the 2nd day after operation,and the observation group was treated with fallopian tube interven-tion and given Self-made Damp-heat Type Pelvic Inflammation Recipe on the 2nd day after operation.The fallopian tube recanali-zation rate,TCM syndromes scores and levels of serum inflammatory factors[interleukin-2(IL-2),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]were counted in the two groups after treatment.After 1year of follow-up,the pregnancy rate and incidence rate of complications were recorded in the two groups.Results:There was no significant difference in the fallo-pian tube recanalization rate between the two groups(P>0.05).After treatment,the scores of TCM symptoms in the observation group were significantly lower than those in the controlled group,and the IL-2level was significantly higher than that in the con-trolled group while the levels of IL-6and TNF-αwere significantly lower than those in the controlled group(P<0.05).The in-trauterine pregnancy rate in the observation group was significantly higher than that in the controlled group while the incidence rate of complications was significantly lower than that in the controlled group(P<0.05).Conclusion:Self-made Damp-heat Type Pel-vic Inflammation Recipe combined with interventional therapy for tubal infertility(damp-heat stagnation type)can quickly relieve the discomfort,promote the fallopian tube recanalization,and effectively improve the pregnancy rate,and its role mechanism may be related to reduction of inflammatory injury,promotion of inflammation absorption and regulation of the body immunity.
作者
杨秀娥
YANG Xiu’e(The People’s Hospital of Hongan County(Huanggang Hubei 438400,China))
出处
《四川中医》
2020年第4期168-171,共4页
Journal of Sichuan of Traditional Chinese Medicine
关键词
湿热型盆腔炎方
介入术
输卵管性不孕
妊娠率
Damp-heat Type Pelvic Inflammation Recipe
Interventional therapy
Tubal infertility
Pregnancy rate
