摘要
目的探讨和分析在小儿肺炎患儿经阿奇霉素序贯治疗中辅以特布他林的临床疗效。方法抽取2018年10月—2019年10月在该院接受治疗的小儿肺炎患儿78例,按照等差数列首项为1,公差为5的方式将78例患者平均分为两组,即对照组和实验组,每组患儿均为39例。对照组患儿进行阿奇霉素序贯治疗,实验组患儿采取特布他林辅助阿奇霉素序贯治疗,观察两组患儿恢复效果,并总结患儿的不良反应。结果实验组患儿治疗总有效率为97.43%,对照组患儿治疗总有效率为79.48%,差异有统计学意义(χ^2=4.137,P<0.05)。实验组患儿总不良反应率为5.12%,对照组患儿总不良反应率为15.38%,差异有统计学意义(χ^2=2.137,P<0.05)。对照组患儿的肿瘤坏死因子α(36.28±3.69)mg/L、白细胞介素6(25.36±1.88)ng/L、超敏C反应蛋白(12.37±4.22)mg/L,实验组患儿的肿瘤坏死因子α(24.33±4.36)mg/L、白细胞介素6(18.33±5.36)ng/L、超敏C反应蛋白(4.18±1.58)mg/L,差异有统计学意义(t=6.884、7.556、11.337,P<0.05)。结论特布他林辅助阿奇霉素序贯治疗小儿肺炎效果显著,能够提高治疗总有效率,降低总不良反应,显著改善炎性因子,降低患者的治疗风险,值得推广。
Objective To investigate and analyze the clinical efficacy of terbutaline in sequential treatment of azithromycin in children with pneumonia.Methods A total of 78 children with pediatric pneumonia who were treated in the hospital from October 2018 to October 2019 were selected,and 78 patients were divided into two groups according to the method of the first order of the difference and the tolerance of 5:the control group and experimental group,there were 39 children in each group.The children in the control group received sequential treatment with azithromycin.The children in the experimental group received terbutaline-assisted sequential treatment with azithromycin.The recovery effects of the two groups were observed and the adverse reactions were summarized.Results The total effective rate of treatment in the experimental group was 97.43%,and the total effective rate in the control group was 79.48%,the difference was statistically significant(χ^2=4.137,P<0.05).The total adverse reaction rate of children in the experimental group was 5.12%,and the total adverse reaction rate of children in the control group was 15.38%,the difference was statistically significant(χ^2=2.137,P<0.05).Tumor necrosis factorα(36.28±3.69)mg/L,interleukin 6(25.36±1.88)ng/L,and high-sensitivity C-reactive protein(12.37±4.22)mg/L in children in the control group.Tumor necrosis factorα(24.33±4.36)mg/L,interleukin 6(18.33±5.36)ng/L,and high-sensitivity C-reactive protein(4.18±1.58)mg/L.The difference was statistically significant(t=6.884,7.556,11.337,P<0.05).Conclusion Terbutaline-assisted azithromycin sequential treatment of pediatric pneumonia has a significant effect,which can improve the total effective rate of treatment,reduce the total adverse reactions,significantly improve the inflammatory factors,and reduce the treatment risk of patients.
作者
苗金美
MIAO Jin-mei(Department of Pediatrics,People's Hospital of Lingcheng District,Dezhou,Shandong Province,253500 China)
出处
《系统医学》
2020年第8期95-97,共3页
Systems Medicine
关键词
特布他林辅助阿奇霉素序贯治疗
小儿肺炎
重要应用
Terbutaline-assisted sequential azithromycin treatment
Pediatric pneumonia
Important application
