摘要
脾虚生痰堵塞脉道是动脉粥样硬化(Atherosclerosis,AS)性疾病发生的主要中医病机。脾虚状态下肠道菌群失调,脾虚生痰脂蛋白亚群分布异常引起脂代谢紊乱。因此从微生物组分改变与脂蛋白亚群分布异常的微观机制探讨脾虚生痰与AS的关系,有助于开辟中西医结合防治AS的新思路。
Spleen deficiency which can cause phlegm and blockage of arteries is the main pathogenesis of atherosclerotic diseases in traditional Chinese medicine.In the state of spleen deficiency,intestinal flora disorder and phlegm caused by spleen deficiency would lead to abnormal distribution of lipoprotein.Therefore,it is helpful to explore the relationship between spleen deficiency causing phlegmand atherosclerosis from the microscopic mechanism of the change of microbial components and abnormal distribution of lipoprotein subgroupsandopen up a new way of prevention and treatment of AS with integrated traditional Chinese and Western medicine.
作者
李鑫
马艺鑫
吕美君
崔馨月
张会永
程岩岩
贾连群
LI Xin;MA Yixin;LYU Meijun;CUI Xinyue;ZHANG Huiyong;CHENG Yanyan;JIA Lianqun(Key Laboratory of Ministry of Education for TCM Viscera-State Theory and Applications,Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China;The First Clinical College of Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)
出处
《中华中医药学刊》
CAS
北大核心
2020年第5期89-91,共3页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金(81774022)
辽宁省高等学校创新团队支持计划(LT2016012)
沈阳市高层次人才创新计划(RC170248)。
关键词
肠道微生物组
脂蛋白亚群
脾虚生痰
动脉粥样硬化
intestinal microorganism group
lipoprotein subgroup
spleen deficiency causing phlegm
atherosclerosis
