摘要
目的观察胺碘酮在急性心肌梗死患者院前急救中的应用效果。方法选取在广宁县人民医院进行院前急救的60例急性心肌梗死患者作为研究对象,按随机数字表法分为对照组(n=30)与观察组(n=30)。对照组采取利多卡因治疗,观察组采取胺碘酮治疗,比较两组治疗有效率、抢救成功率、再梗死率、心功能指标水平及不良反应发生率。结果观察组治疗有效率为96.67%,明显高于对照组的73.33%,差异有统计学意义(P<0.05);观察组抢救成功率明显高于对照组,再梗死率明显低于对照组,差异均有统计学意义(P<0.05);治疗后观察组左心室射血分数(left ventricular ejection fractions,LVEF)明显高于对照组,左心室舒张末容积(left ventricular end-diastolic volume,LVEDV)、左心室收缩末容积(left ventricular end-systolic volume,LVESV)均明显低于对照组,差异均有统计学意义(P<0.05)。结论胺碘酮应用在急性心肌梗死患者的院前急救中,可提高抢救成功率,降低再梗死率和改善心功能指标水平的效果优于利多卡因效果。
Objective To observe effects of amiodarone in pre-hospital emergency treatment of patients with acute myocardial infarction.Methods 60 patients with acute myocardial infarction,who undergone pre-hospital emergency treatment in Guangning County People's Hospital,were selected as the research subjects,and divided into a control group(n=30)and an observation group(n=30)according to random number table method.The control group was treated with lidocaine,while the observation group was treated with amiodarone.Then,the treatment effective rate,rescue success rate,reinfarction rate,heart function index levels and adverse reaction rate were compared between the two groups.Results The effective rate in the observation group was 96.67%,which was significantly higher than 73.33%of the control group,and the difference was statistically significant(P<0.05).The rescue success rate of the observation group was significantly higher than that of the control group;the reinfarction rate was significantly lower than that of the control group,and the differences were statistically significant(P<0.05).After treatment,the left ventricular ejection fraction(LVEF)of the observation group was significantly higher than that of the control group,left ventricular end-diastolic volume(LVEDV)and left ventricular end-systolic volume(LVESV)were significantly lower than those of the control group,and the differences were statistically significant(P<0.05).Conclusions The application of amiodarone in the pre-hospital emergency treatment of acute myocardial infarction can increase the rescue success rate,reduce the reinfarction rate,and improve the heart function index levels.Moreover,it is superior to lidocaine.
作者
梁文权
LIANG Wenquan(Emergency Department,Guangning County People's Hospital,Zhaoqing 526300,China)
出处
《中华灾害救援医学》
2020年第7期361-363,共3页
Chinese Journal of Disaster Medicine
基金
肇庆市科技创新指导类项目(201904030760)。
关键词
胺碘酮
利多卡因
急性心肌梗死
院前急救
效果
amiodarone
lidocaine
acute myocardial infarction
pre-hospital emergency treatment
effect
