摘要
目的分析腹膜透析(PD)患者的贫血状况及相关危险因素。方法选择2011年3月至2017年6月于安徽医科大学第一附属医院肾内科行规律PD治疗1年内的患者186例为研究对象,收集其一般临床资料及实验室检查资料。根据Hb水平将患者分为对照组(Hb≥110 g/L)与贫血组(Hb<110 g/L)。分析影响PD患者合并贫血的危险因素。结果186例PD患者中,合并贫血127例,发生率为68.28%。单因素分析显示,贫血组血清白蛋白及血肌酐水平低于对照组,可溶性转铁蛋白受体水平显著高于对照组(P<0.05)。多因素Logistic回归分析结果提示,血肌酐水平<884μmol/L和血清白蛋白水平<35 g/L是影响PD患者合并贫血的独立危险因素(P<0.05)。结论血肌酐水平过低和低蛋白血症是影响PD患者发生贫血的独立危险因素。
Objective To analyze the anemia status and related risk factors of patients with peritoneal dialysis(PD).Methods One hundred and eighty-six patients with regular PD treatment within one year in the nephrology department of the first affiliated hospital of Anhui medical university from March 2011 to June 2017 were selected as the research objects,and the general clinical data and laboratory examination data were collected.According to the level of Hb,the patients were divided into control group(Hb≥110 g/L)and anemia group(Hb<110 g/L).The risk factors of anemia in PD patients were analyzed.Results Among 186 cases of PD patients,127 cases were complicated with anemia,and the incidence was 68.28%.The univariate analysis showed that the levels of serum albumin and serum creatinine in the anemia group were lower than those in the control group,while the level of soluble transferrin receptor was significantly higher than that in the control group(P<0.05).The multivariate Logistic regression analysis showed that serum creatinine level<884μmol/L and serum albumin level<35 g/L were independent risk factors of anemia in PD patients(P<0.05).Conclusion Low serum creatinine and hypoproteinemia are independent risk factors for anemia in PD patients.
作者
任琳
王坤
王金霞
吴永贵
REN Lin;WANG Kun;WANG Jin-xia;WU Yong-gui(Nephrology Department,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)
出处
《临床医学研究与实践》
2020年第21期18-20,共3页
Clinical Research and Practice
关键词
腹膜透析
肾性贫血
血肌酐
低蛋白血症
peritoneal dialysis
renal anemia
serum creatinine
hypoproteinemia
