摘要
目的探讨美托洛尔辅助治疗糖尿病合并甲亢的临床效果。方法纳入我院80例2017年2月14日至2018年1月11日糖尿病合并甲亢患者。随机数字表分组,常规控制组采取常规药物治疗,美托洛尔治疗组则采取常规药物加上美托洛尔治疗。比较常规控制组、美托洛尔治疗组疗效;空腹血糖控制在6.1 mmol/L以下的时间、餐后2 h血糖控制在7.8 mmol/L以下的时间;治疗前后患者甲状腺的相关指标;不良反应。结果美托洛尔治疗组疗效、空腹血糖控制在6.1 mmol/L以下的时间、餐后2 h血糖控制在7.8 mmol/L以下的时间、甲状腺的相关指标相比较常规控制组更好,P <0.05。美托洛尔治疗组不良反应和常规控制组无明显差异,P> 0.05。结论常规药物加上美托洛尔治疗糖尿病合并甲亢的效果理想。
Objective To investigate the clinical effect and safety of donepezil in the treatment of alzheimer’s disease. Methods 88 patients with alzheimer’s disease were enrolled in our hospital from July 2014 to August 2012. The random number table was divided into two groups: the conventional drug therapy intervention group received conventional drug therapy, and the conventional drug therapy intervention group combined with donepezil received conventional drug therapy plus donepezil treatment. To compare the effects of conventional drug therapy intervention group, conventional drug therapy intervention group combined with donepezil treatment group;Duration of cognitive improvement, length of hospital stay;Before and after treatment, MMSE scores of cognitive function and ADL scores of self-care ability of patients were measured. The adverse event. Results Compared with the conventional drug therapy intervention group, the effect, duration of cognitive improvement, length of hospital stay, MMSE score of cognitive function and ADL score of self-care ability were better in the conventional drug therapy intervention group(P<0.05). There was no significant difference in side effects between the conventional drug therapy intervention group and the conventional drug therapy intervention group(P>0.05). Conclusion Conventional drugs combined with donepezil are effective in the treatment of alzheimer’s disease.
作者
吕金龙
LV Jin-long(Huludao Central Hospital,Huludao 125000,China)
出处
《中国医药指南》
2020年第21期57-58,共2页
Guide of China Medicine
关键词
美托洛尔辅助
糖尿病合并甲亢
临床效果
Metoprolol assist
Diabetes with hyperthyroidism
Clinical effect