摘要
目的:探讨经阴道彩色多普勒超声定量参数对宫颈癌患者的诊断和临床价值。方法:2013年6月至2018年6月期间,回顾性收集我院收治的宫颈癌患者32例作为观察组,同期随机抽取至我院健康体检的成年女性32例作为对照组。观察两组经阴道彩色多普勒超声定量参数差异,同时分析超声定量参数与TNM分期、肿瘤体积的相关性。结果:与对照组比较,观察组收缩峰值流速降低(0.51±0.14 vs 0.72±0.12,P=0.000);舒张末期流速增加(12.73±3.87 vs 8.67±4.01,P=0.000);阻力指数增加(6.34±2.62 vs 3.02±1.04,P=0.000);血管形成指数增加(4.12±1.82 vs 1.03±0.34,P=0.000);血流指数增加(41.37±4.82 vs 37.92±5.12,P=0.007);血管形成-血流指数增加(2.35±1.04 vs 0.82±0.36,P=0.000)。宫颈癌患者肿瘤体积与收缩峰值流速显著负相关,与舒张末期流速、阻力指数、血管形成指数、血流指数、血管形成-血流指数显著正相关(P<0.05)。与Ⅰ期或Ⅱ期的患者相比,Ⅲ期或Ⅳ期的患者收缩峰值流速降低(0.43±0.12 vs 0.56±0.15,P=0.016);舒张末期流速增加(13.92±2.94 vs 12.02±2.23,P=0.047);阻力指数增加(7.52±2.42 vs 5.63±2.07,P=0.026);血管形成指数增加(5.51±1.67 vs 3.29±1.92,P=0.002);血流指数增加(49.82±5.58 vs 36.30±6.62,P=0.000);血管形成-血流指数增加(3.01±1.27 vs 1.95±1.48,P=0.048)。结论:经阴道彩色多普勒超声定量参数可以较好反应宫颈癌患者局部血流情况,对早期诊断宫颈癌具有一定价值,且与宫颈癌患者临床分期有关。
Objective:To investigate the diagnosis and clinical value of quantitative parameters of transvaginal color Doppler ultrasound in cervical cancer.Methods:From June 2013 to June 2018,32 patients with cervical cancer in our hospital were retrospectively collected as an observation group,and 32 adult women who were randomly selected for health examination in our hospital as a control group during the same period.The differences of quantitative parameters of transvaginal color Doppler ultrasound between the two groups were observed,and the correlation between quantitative parameters of transvaginal color Doppler ultrasound and TNM staging,tumor volume was analyzed.Result:When compared with the control group,the peak systolic flow velocity in the observation group decreased(0.51±0.14 vs 0.72±0.12,P=0.000).the end diastolic flow velocity increased(12.73±3.87 vs 8.67±4.01,P=0.000),the resistance index increased(6.34±2.62 vs 3.02±1.04,P=0.000),the angiogenesis index increased(4.12±1.82 vs 1.03±0.34,P=0.000),and the blood flow index increased(41.37±4.82 vs 37.92±5.12,P=0.007),the angiogenesis-blood flow index increased(2.35±1.04 vs 0.82±0.36,P=0.000).Tumor volume was negatively correlated with peak systolic flow rate,and positively correlated with end-diastolic flow rate,resistance index,angiogenesis index,blood flow index and angiogenesis-blood flow index(P<0.05).When compared with patients in stage I or II,peak systolic velocity in stage III or IV decreased(0.43±0.12 vs 0.56±0.15,P=0.016),end diastolic velocity increased(13.92±2.94 vs 12.02±2.23,P=0.047),resistance index increased(7.52±2.42 vs 5.63±2.07,P=0.026),and angiogenesis index increased(5.51±1.67 vs 3.29±1.92,P=0.002),the blood flow index increased(49.82±5.58 vs 36.30±6.62,P=0.000),and the angiogenesis-blood flow index increased(3.01±1.27 vs 1.95±1.48,P=0.048).Conclusion:Quantitative parameters of transvaginal color Doppler ultrasound can better reflect the local blood flow of cervical cancer patients,which has certain value for early diagnosis of cervical cancer,and is related to clinical stage of cervical cancer patients.
作者
王晓燕
李小飞
马英超
Wang Xiaoyan;Li Xiaofei;Ma Yingchao(Health and Physical Examination Center,Beijing Shijitan Hospital,Beijing 100038,China;Department of Ultrasound,Shougang Hospital,Peking University,Beijing 100144,China.)
出处
《现代肿瘤医学》
CAS
2020年第16期2861-2865,共5页
Journal of Modern Oncology
关键词
经阴道彩色多普勒超声
定量参数
宫颈癌
transvaginal color Doppler ultrasound
quantitative parameters
cervical cancer
