摘要
目的:探讨温州地区2019冠状病毒病(COVID-19)患者的临床特征及中医证候分布规律,为中医辨证论治提供参考依据。方法:收集温州市各定点医院255例COVID-19患者的一般资料、C-反应蛋白(CRP)、血常规、胸部CT、症候特征、舌象等信息,总结COVID-19患者的中医证候分布情况。结果:COVID-19患者平均年龄在(50.50±15.19)岁,男女比例为1∶0.69,75例(29.41%)患者有武汉/湖北旅居史,177例(69.41%)患者有确诊患者密切接触史,118例(46.27%)患者合并基础疾病;147例(57.65%)患者CRP升高,45例(17.65%)患者白细胞计数下降,64例(25.10%)患者淋巴细胞计数下降;195例(77.69%)患者肺部CT以多肺叶病灶为主;症候特征以发热(83.14%)、咳嗽(49.02%)、乏力(41.18%)为主;舌质以淡红舌(57.65%)、红舌(40.78%)为主,舌苔以腻苔(84.31%)为主;中医证型依次为疫毒闭肺证136例(53.33%)、湿毒蕴肺证98例(38.43%)、气血两燔证16例(6.27%)、内闭外脱证5例(1.96%)。结论:温州地区COVID-19患者的中医证型分布具有一定规律,以疫毒闭肺证、湿毒蕴肺证为主,疫毒夹湿是主要病因。
Objective:To study clinical characteristics and traditional Chinese medicine(TCM)syndrome in patients with Corona Virus Disease 2019(COVID-19)in Wenzhou,and to provide a basis for clinical diagnosis and treatment.Methods:A total of 255 COVID-19 cases were collected from designated hospitals,to collect the general data,C-reactive protein,blood routine,chest CT,syndrome characteristics,tongue image and other information,and then to summarize syndrome distribution characteristics of COVID-19 patients.Results:The mean age of all patients was(50.50±15.19)years,the ratio of male to female was 1∶0.69,75 cases(29.41%)of them had the history of visiting or living in Wuhan/Hubei,177 cases(69.41%)of them had the history of close contact with the confirmed patients,118 case(46.27%)of them had underlying diseases,147 cases(57.65%)of them had C-reactive protein increased,45 cases(17.65%)of them had numeration of leukocyte decreased,64 cases(25.10%)of them had lymphocyte count decreased.There were 195 cases(77.69%)of patients mainly showing chest CT two lobar lesions.The main clinical manifestations included fever(83.14%),cough(49.02%),and fatigue(41.18%).Light red tongue(57.65%)and red tongue(40.78%)were dominant in tongue quality,with mainly greasy coating(84.31%).TCM syndrome types were epidemic virus closed lung of 136 cases(53.33%),wet poison accumulate lung of 98 cases(38.43%),dual blaze of qi-blood aspects of 16 cases(6.27%),and internal block and external collapse of 5 cases(1.96%)in sequence.Conclusion:The distribution of TCM syndrome of patients with COVID-19 in Wenzhou has certain regularity,epidemic virus closed lung and wet poison accumulate lung are the common TCM syndromes,the epidemic virus with dampness is the main pathogeny.
作者
潘晓琼
袁拯忠
陈捷
叶人
朱文宗
杨军
程锦国
PAN Xiao-qiong;YUAN Zheng-zhong;CHEN Jie;YE Ren;ZHU Wen-zong;YANG Jun;CHENG Jin-guo(The Second Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China;The First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325015,China;Wenzhou Chinese Medicine Hospital,Wenzhou 325000,China;Wenzhou Central Hospital,Wenzhou 325000,China;Wenzhou Medical College,Wenzhou 325035,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2020年第6期3199-3202,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
温州市新型冠状病毒肺炎疫情防控应急攻关项目(No.ZY202003)。
关键词
2019冠状病毒病
新型冠状病毒肺炎
临床特征
中医证候
温州
瘟疫
疫毒闭肺
湿毒蕴肺
Corona Virus Disease 2019(COVID-19)
Novel Coronavirus Pneumouia(NCP)
Clinical characteristics
TCM syndrome
Wenzhou
Plague
Epidemic virus closed lung
Wet poison accumulate lung
