摘要
目的探讨氧气雾化吸入联合无创咳痰机治疗肺尘埃沉着病肺灌洗术后效果。方法回顾性分析我院2018年6月~2019年12月行小容量肺灌洗治疗的80例肺尘埃沉着病患者临床资料,按治疗方式不同分为A组(40例)、B组(40例)。A组行氧气雾化吸入联合无创咳痰机治疗,B组行单一氧气雾化吸入治疗。比较两组治疗5 d后的肺功能、血气分析指标及临床症状评分。结果 A组一氧化碳弥散量(DLCO)、第1秒用力呼出量(FEV1)、肺总量(TLC)水平为(8.34±1.65)mmol/(min·kPa)、(4.55±0.77)L、(8.71±2.12)L,高于B组[DLCO:(7.24±2.82)mmol/(min·kPa)、FEV1:(3.89±1.16)L、TLC:(7.52±1.67)L],差异有统计学意义(P<0.05);A组血氧饱和度(SaO_2)、氧分压(PaO_2)水平为(96.12±3.15)%、(97.42±8.07)mmHg,高于B组[SaO_2:(93.17±5.68)%、PaO_2:(91.37±6.64)mmHg],差异有统计学意义(P<0.05);A组临床症状评分为(1.75±0.62)分,低于B组[(2.56±1.01)分],差异有统计学意义(P<0.05)。结论氧气雾化吸入联合无创咳痰机治疗可减轻肺尘埃沉着病肺灌洗术后临床症状,改善肺功能、血气分析指标,提高患者对肺灌洗的耐受能力,利于术后早期恢复。
Objective To explore the effect of oxygen atomization inhalation combined with non-invasive expectoration machine in the treatment of pneumoconiosis.Methods The clinical data of 80 patients with pneumoconiosis who were treated with small volume lung lavage from June 2018 to December 2019 were analyzed retrospectively.According to the different treatment methods,they were divided into group A(40 cases)and group B(40 cases).Group A was treated with oxygen atomization inhalation combined with non-invasive expectoration machine,and group B with single oxygen atomization inhalation.The lung function,blood gas analysis index and clinical symptom score of the two groups were compared after 5 days of treatment.Results Carbon monoxide dispersion(DLCO),forced expiratory volume in 1 second(FEV1),total lung(TLC)levels in group A were(8.34±1.65)mmol/(min·kPa),(4.55±0.77)L,(8.71±2.12)L,higher than group B(DLCO:[7.24±2.82]mmol/(min·kPa),FEV1:[3.89±1.16]L,TLC:[7.52±1.67]L),the differences were statistically significant(P<0.05).Blood oxygen saturation(SaO2),oxygen partial pressure(PaO2)levels in Group A were(96.12±3.15)%,(97.42±8.07)mmHg,higher than group B(SaO2:[93.17±5.68]%,PaO2:[91.37±6.64]mmHg),the differences were statistically significant(P<0.05);the clinical symptom score of group A was(1.75±0.62)points,which was lower than that of group B([2.56±1.01]points),the difference was statistically significant(P<0.05).Conclusion The combination of oxygen atomization inhalation and non-invasive expectoration machine can reduce the clinical symptoms,improve the lung function and blood gas analysis index,improve the patients′tolerance to lung lavage,and facilitate the early recovery.
作者
戴连英
赵彬
符春生
DAI Lian-ying;ZHAO Bin;FU Chun-sheng(Department of Rehabilitation Medicine,Shaoguan Occupational Disease Prevention and Control Institute,Guangdong Province,Shaoguan512028,China)
出处
《中国当代医药》
2020年第22期34-36,40,共4页
China Modern Medicine
基金
广东省韶关市卫生科研基金项目(Y20028)。
关键词
肺尘埃沉着病
氧气雾化吸入
肺灌洗术
无创咳痰机
肺功能
Pneumoconiosis
Oxygen atomization inhalation
Lung lavage
Noninvasive expectoration machine
Lung function
